Detailed information NTG0683376

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: NOV96_RS10665
• Genome accession: NZ_CP110141
• Coordinates: 2162591..2165131 (-)
• Length: 846 a.a.
• NCBI ID: WP_002937034.1
• Uniprot ID: -
• Organism: Streptococcus suis strain WUSS030
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2157591..2170131

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NOV96_RS10640 (NOV96_10640)	vraR	2158069..2158710 (-)	642	WP_002937025.1	response regulator transcription factor	Regulator
NOV96_RS10645 (NOV96_10645)	-	2158682..2159698 (-)	1017	WP_002937028.1	sensor histidine kinase	-
NOV96_RS10650 (NOV96_10650)	liaF	2159695..2160354 (-)	660	WP_225585639.1	cell wall-active antibiotics response protein LiaF	-
NOV96_RS10655 (NOV96_10655)	-	2160795..2162084 (-)	1290	WP_002935134.1	IS4-like element ISSsu2 family transposase	-
NOV96_RS10660 (NOV96_10660)	-	2162150..2162338 (-)	189	WP_002937032.1	hypothetical protein	-
NOV96_RS10665 (NOV96_10665)	hexA	2162591..2165131 (-)	2541	WP_002937034.1	DNA mismatch repair protein MutS	Machinery gene
NOV96_RS10670 (NOV96_10670)	argR	2165146..2165586 (-)	441	WP_002937036.1	arginine repressor	-
NOV96_RS10675 (NOV96_10675)	argS	2165693..2167381 (+)	1689	WP_002937037.1	arginine--tRNA ligase	-
NOV96_RS10680 (NOV96_10680)	-	2167561..2168475 (+)	915	WP_002937039.1	SH3 domain-containing protein	-
NOV96_RS10685 (NOV96_10685)	-	2168529..2169050 (-)	522	WP_002937042.1	hypothetical protein	-
NOV96_RS10690 (NOV96_10690)	-	2169162..2169344 (+)	183	WP_002937045.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95044.55 Da
• Isoelectric Point: 4.8211

>NTDB_id=683376 NOV96_RS10665 WP_002937034.1 2162591..2165131(-) (hexA) [Streptococcus suis strain WUSS030]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAIVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILQQINEPALGNLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVIREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPTTPAPIVV
EEPSGQIDLFADTPSHPVLDELAKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=683376 NOV96_RS10665 WP_002937034.1 2162591..2165131(-) (hexA) [Streptococcus suis strain WUSS030]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAATTATTTTATGAAGATGCGGTAGAAGCGGCACAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAAAATCCGATTCCTATGGCGGGGGTACCGTATCACGCGGCACAACAGTATATCGACACACTTGTT
GAACTGGGTCATAAGGTCGCTATTGCTGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
ACAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGATAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTGCAGTTTGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAGATCCGCAATTTACGGGCACGTGAATTGGTCATCGGCTATGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCAAACCAGATGAACCTCCTACTCTCTTTTGAAGATGAGGTGACAGAGGATGTCCAATTGATTGATAACTCCTTGACAG
ATTTGGAAAAGGCTGCGGCGGGCAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTCCACTATGAAATCAAGGACTATCTGCAAATGGACTATGCAACCAAGTCCAGTCTGGACCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGTTAGACGAAACTAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGACCTTAAGCGGATTGAGAATCGTCAGGCTATCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTTGAAGCTTTAAAAGGTGTCTATGACATCGAACGCTTGGCTAGCCGGGTATCTTTTGGAAAAAC
CATGCCAAAGGATCTCTTGCAGCTCTCCCAGACTCTGGGAAATATCCCAGCAATCAAGAATATCTTGCAACAAATCAATG
AGCCTGCTCTAGGCAATTTGGTGGCTGGATTGGACCCAATCCCAGAACTGCACGCTCTCATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACCATCACAGATGGAAACATCATCCGTACGGGCTTTGATGAAACGCTGGATCAGTATCGTCTGGTCAT
TCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCTAAGGAGCGTGAAGCGTCTGGTATCAATAATCTTAAGATTGATT
ACAATAAAAAAGACGGTTACTATTTCCATGTTACCAATTCCAATCTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGCTATGGAACGGAAGAGTTGGCTAAGATTGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATAGGTCGCTTGCAGAAGCTGGCTC
GGACCATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGAATACCGATACGCATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACTCGTATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAAATGATGGAGGCCAATAA
GGCAGTCCGTCTGGCGACAGATCGGTCACTCATCCTCTTTGATGAGTTGGGGCGGGGAACGGCCACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAGTACATCCACGACAAGATTGGAGCCAAGACTCTCTTTGCTACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACCTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGTCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAACTAT
TGCAGCGGGCGGACAGGATTTTGCAGACGCTTGAAAACCAAGCTCCTACTGCACCAACTACCCCAGCTCCGATAGTCGTG
GAAGAGCCGTCTGGTCAAATCGACCTCTTCGCAGACACGCCTTCTCACCCAGTCCTCGATGAACTGGCAAAACTGGATAT
CTACAATATGACCCCTATGGAAGTCATGATGGCAGTGGCGGAGTTGAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.995	100	0.74
mutS	Pseudomonas stutzeri strain ATCC 17587	37.747	100	0.384