Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   NOV96_RS10640 Genome accession   NZ_CP110141
Coordinates   2158069..2158710 (-) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain WUSS030     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2153069..2163710
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NOV96_RS10620 (NOV96_10620) - 2154392..2155063 (+) 672 WP_240016924.1 site-specific integrase -
  NOV96_RS10625 (NOV96_10625) cysK 2155293..2156219 (+) 927 WP_002937015.1 cysteine synthase A -
  NOV96_RS10630 (NOV96_10630) - 2156246..2156617 (-) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  NOV96_RS10635 (NOV96_10635) - 2156619..2158019 (-) 1401 WP_002937018.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  NOV96_RS10640 (NOV96_10640) vraR 2158069..2158710 (-) 642 WP_002937025.1 response regulator transcription factor Regulator
  NOV96_RS10645 (NOV96_10645) - 2158682..2159698 (-) 1017 WP_002937028.1 sensor histidine kinase -
  NOV96_RS10650 (NOV96_10650) liaF 2159695..2160354 (-) 660 WP_225585639.1 cell wall-active antibiotics response protein LiaF -
  NOV96_RS10655 (NOV96_10655) - 2160795..2162084 (-) 1290 WP_002935134.1 IS4-like element ISSsu2 family transposase -
  NOV96_RS10660 (NOV96_10660) - 2162150..2162338 (-) 189 WP_002937032.1 hypothetical protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=683375 NOV96_RS10640 WP_002937025.1 2158069..2158710(-) (vraR) [Streptococcus suis strain WUSS030]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=683375 NOV96_RS10640 WP_002937025.1 2158069..2158710(-) (vraR) [Streptococcus suis strain WUSS030]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCTAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCCGCTATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCTTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413