Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   M0696_RS06345 Genome accession   NZ_CP096590
Coordinates   1256848..1257504 (+) Length   218 a.a.
NCBI ID   WP_014113374.1    Uniprot ID   G4NWF3
Organism   Bacillus rugosus strain A78.1     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1251848..1262504
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M0696_RS06315 (M0696_06315) oppF 1252300..1253217 (+) 918 WP_166853628.1 oligopeptide ABC transporter ATP-binding protein OppF -
  M0696_RS06320 (M0696_06320) - 1253323..1254537 (+) 1215 WP_222142934.1 MFS transporter -
  M0696_RS06325 (M0696_06325) - 1254717..1255295 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  M0696_RS06330 (M0696_06330) spx 1255476..1255871 (+) 396 WP_003239281.1 transcriptional regulator Spx -
  M0696_RS06335 (M0696_06335) - 1255914..1256570 (-) 657 WP_166853627.1 TerC family protein -
  M0696_RS06340 (M0696_06340) - 1256756..1256881 (+) 126 WP_120698858.1 hypothetical protein -
  M0696_RS06345 (M0696_06345) mecA 1256848..1257504 (+) 657 WP_014113374.1 adaptor protein MecA Regulator
  M0696_RS06350 (M0696_06350) - 1257499..1257619 (-) 121 Protein_1188 hypothetical protein -
  M0696_RS06355 (M0696_06355) coiA 1257663..1258814 (+) 1152 WP_222142601.1 competence protein CoiA family protein Machinery gene
  M0696_RS06360 (M0696_06360) pepF 1259044..1260873 (+) 1830 WP_166854689.1 oligoendopeptidase F -
  M0696_RS06365 (M0696_06365) - 1260910..1261077 (-) 168 WP_019713977.1 hypothetical protein -
  M0696_RS06370 (M0696_06370) spxH 1261391..1262290 (-) 900 WP_166853625.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25730.60 Da        Isoelectric Point: 4.1174

>NTDB_id=681942 M0696_RS06345 WP_014113374.1 1256848..1257504(+) (mecA) [Bacillus rugosus strain A78.1]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFGNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=681942 M0696_RS06345 WP_014113374.1 1256848..1257504(+) (mecA) [Bacillus rugosus strain A78.1]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGAAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAGGAAGAGGAAT
TTGCTGTGGAAGGCCCTCTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGGTTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATACTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTGGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTGGAAACAATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G4NWF3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991