Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N8A71_RS10100 Genome accession   NZ_CP109929
Coordinates   2158876..2159532 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O6:K2:H1 strain C 691-04A     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2153876..2164532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N8A71_RS10070 (N8A71_10070) dcyD 2154755..2155741 (+) 987 WP_001128236.1 D-cysteine desulfhydrase -
  N8A71_RS10075 (N8A71_10075) tcyL 2155756..2156424 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  N8A71_RS10080 (N8A71_10080) tcyN 2156421..2157173 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N8A71_RS10085 (N8A71_10085) sdiA 2157403..2158125 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  N8A71_RS10090 (N8A71_10090) yecF 2158193..2158417 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  N8A71_RS10095 (N8A71_10095) yecU 2158404..2158580 (-) 177 WP_001304283.1 protein YecU -
  N8A71_RS10100 (N8A71_10100) letA 2158876..2159532 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N8A71_RS10105 (N8A71_10105) uvrC 2159529..2161361 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  N8A71_RS10110 (N8A71_10110) pgsA 2161418..2161966 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N8A71_RS10130 (N8A71_10130) yecA 2162615..2163280 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=681879 N8A71_RS10100 WP_000611328.1 2158876..2159532(+) (letA) [Escherichia coli O6:K2:H1 strain C 691-04A]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=681879 N8A71_RS10100 WP_000611328.1 2158876..2159532(+) (letA) [Escherichia coli O6:K2:H1 strain C 691-04A]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482