Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N8A72_RS10105 Genome accession   NZ_CP109924
Coordinates   2083277..2083933 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O125ac:K+:H10 strain C 236-04A     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2078277..2088933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N8A72_RS10075 (N8A72_10075) dcyD 2079157..2080143 (+) 987 WP_001128238.1 D-cysteine desulfhydrase -
  N8A72_RS10080 (N8A72_10080) tcyL 2080158..2080826 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  N8A72_RS10085 (N8A72_10085) tcyN 2080823..2081575 (+) 753 WP_016240022.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N8A72_RS10090 (N8A72_10090) sdiA 2081805..2082527 (+) 723 WP_016243617.1 transcriptional regulator SdiA -
  N8A72_RS10095 (N8A72_10095) yecF 2082594..2082818 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  N8A72_RS10100 (N8A72_10100) yecU 2082805..2082981 (-) 177 WP_001307856.1 protein YecU -
  N8A72_RS24500 - 2083064..2083135 (-) 72 Protein_1981 transcriptional regulator -
  N8A72_RS10105 (N8A72_10105) letA 2083277..2083933 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N8A72_RS10110 (N8A72_10110) uvrC 2083930..2085762 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  N8A72_RS10115 (N8A72_10115) pgsA 2085819..2086367 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N8A72_RS10135 (N8A72_10135) yecA 2087017..2087682 (+) 666 WP_115207711.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=681791 N8A72_RS10105 WP_000611335.1 2083277..2083933(+) (letA) [Escherichia coli O125ac:K+:H10 strain C 236-04A]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=681791 N8A72_RS10105 WP_000611335.1 2083277..2083933(+) (letA) [Escherichia coli O125ac:K+:H10 strain C 236-04A]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486