Detailed information NTG0681741

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: N7L43_RS22460
• Genome accession: NZ_CP109921
• Coordinates: 4660213..4661238 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli O2:K2:H1 strain C 237-04
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4655213..4666238

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N7L43_RS22440 (N7L43_22440)	metJ	4656398..4656715 (+)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-
N7L43_RS22445 (N7L43_22445)	yiiX	4656775..4657383 (+)	609	WP_000702296.1	YiiX family permuted papain-like enzyme	-
N7L43_RS22450 (N7L43_22450)	rpmE	4657444..4657656 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
N7L43_RS22455 (N7L43_22455)	priA	4657859..4660057 (+)	2199	WP_001305041.1	primosomal protein N'	Machinery gene
N7L43_RS22460 (N7L43_22460)	cytR	4660213..4661238 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
N7L43_RS22465 (N7L43_22465)	ftsN	4661330..4662289 (+)	960	WP_000068846.1	cell division protein FtsN	-
N7L43_RS22470 (N7L43_22470)	hslV	4662382..4662912 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
N7L43_RS22475 (N7L43_22475)	hslU	4662922..4664253 (+)	1332	WP_001293344.1	HslU--HslV peptidase ATPase subunit	-
N7L43_RS22480 (N7L43_22480)	menA	4664320..4665246 (+)	927	WP_001305044.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
N7L43_RS22485 (N7L43_22485)	rraA	4665339..4665824 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
N7L43_RS22490 (N7L43_22490)	zapB	4665909..4666154 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=681741 N7L43_RS22460 WP_000644904.1 4660213..4661238(+) (cytR) [Escherichia coli O2:K2:H1 strain C 237-04]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=681741 N7L43_RS22460 WP_000644904.1 4660213..4661238(+) (cytR) [Escherichia coli O2:K2:H1 strain C 237-04]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACTCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCACAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACTATTCTGGTGATTGTCCCGGATATCTGCGACCCT
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTACCTACAGTTCATATAGACAATCTGACCGCCGCATTTGATGCAGTAAATTATCTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGTTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628