Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   MU858_RS06045 Genome accession   NZ_CP095874
Coordinates   1163990..1164673 (+) Length   227 a.a.
NCBI ID   WP_000350711.1    Uniprot ID   A0A2B0Y2P9
Organism   Bacillus sp. PGP15     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1158990..1169673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MU858_RS06025 (MU858_06025) - 1160056..1161702 (+) 1647 WP_247998856.1 peptide ABC transporter substrate-binding protein -
  MU858_RS06030 (MU858_06030) - 1161730..1161933 (-) 204 WP_000559976.1 hypothetical protein -
  MU858_RS06035 (MU858_06035) spx 1162528..1162923 (+) 396 WP_000258267.1 transcriptional regulator Spx -
  MU858_RS06040 (MU858_06040) - 1162973..1163647 (-) 675 WP_071757024.1 TerC family protein -
  MU858_RS06045 (MU858_06045) mecA 1163990..1164673 (+) 684 WP_000350711.1 adaptor protein MecA Regulator
  MU858_RS06050 (MU858_06050) - 1164746..1166290 (+) 1545 WP_048526701.1 cardiolipin synthase -
  MU858_RS06055 (MU858_06055) - 1166371..1167615 (+) 1245 WP_247998857.1 competence protein CoiA family protein -
  MU858_RS06060 (MU858_06060) pepF 1167666..1169492 (+) 1827 WP_048526703.1 oligoendopeptidase F Regulator

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26965.02 Da        Isoelectric Point: 3.9986

>NTDB_id=678996 MU858_RS06045 WP_000350711.1 1163990..1164673(+) (mecA) [Bacillus sp. PGP15]
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFENRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Nucleotide


Download         Length: 684 bp        

>NTDB_id=678996 MU858_RS06045 WP_000350711.1 1163990..1164673(+) (mecA) [Bacillus sp. PGP15]
TTGGATATTGAAAGAATTAATGACCATACGATGAAATTTTTTATTACGTACATTGATATAGAGGACAGAGGCTTTAATCG
TGAGGAGATTTGGTACGACCGCGAAAGAAGCGAAGAGCTCTTTTGGGAAATGATGGACGAAGCTCGTGATCATGACGATT
TCTTTATTGATGGACCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAAAGCAGAGCTT
TCAAAGGATGGACAAAAGTTAGAACTACCTATAGGTGTAGATAAAATTATAGACATTCCGTTAGATGAAGGCATTGAATC
ATTATTCCAGCAAGAATTAGTGGAAGAGGTAGAAGAACAAGCAGGCACAAACTTTAACGAAGATGGTACGTTTGGCTTTT
TAATTAAGTTTAATGATTTTGAAGATGTCATATCATTAAGCCACCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGAACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAGGAAGAAATTGATCGTATTTTAAG
TATTGTTTTAGAATACGGAGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGAAAACAAATTGTGAAAGAGC
ATGCACTTGAAACAATTCGCAATAATTTTCCTGCTAAAACGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2B0Y2P9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

56.579

100

0.568