Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG428_RS26705 Genome accession   NZ_CP109508
Coordinates   5786193..5786870 (+) Length   225 a.a.
NCBI ID   WP_147984069.1    Uniprot ID   A0ABU8A8V5
Organism   Streptomyces sp. NBC_01422     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5781193..5791870
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG428_RS26685 (OG428_26685) - 5781584..5781817 (-) 234 WP_014153643.1 hypothetical protein -
  OG428_RS26690 (OG428_26690) - 5782250..5784376 (+) 2127 WP_124275054.1 DNA topoisomerase IV subunit B -
  OG428_RS26695 (OG428_26695) - 5784497..5785036 (+) 540 WP_206432606.1 DUF1453 domain-containing protein -
  OG428_RS26700 (OG428_26700) - 5785033..5786196 (+) 1164 WP_329044407.1 histidine kinase -
  OG428_RS26705 (OG428_26705) vraR 5786193..5786870 (+) 678 WP_147984069.1 response regulator transcription factor Regulator
  OG428_RS26710 (OG428_26710) - 5787000..5787440 (+) 441 WP_147984426.1 DUF485 domain-containing protein -
  OG428_RS26715 (OG428_26715) - 5787437..5789029 (+) 1593 WP_124275057.1 cation acetate symporter -
  OG428_RS26720 (OG428_26720) - 5789046..5789723 (-) 678 WP_147984070.1 response regulator -
  OG428_RS26725 (OG428_26725) - 5789720..5791444 (-) 1725 WP_319353548.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 23722.16 Da        Isoelectric Point: 5.7019

>NTDB_id=678142 OG428_RS26705 WP_147984069.1 5786193..5786870(+) (vraR) [Streptomyces sp. NBC_01422]
MSARVVVADDQSVVREGIVMLLGLLPGIEVVGAAKDGDEAVALVAEMSPDVVLMDLRMPRCDGVEATRRIRREHPGTQVV
VLTTFADDDSLFTALQAGARGYLTKDARGEEIAQAIQAVLSGEAGLSPKVQSRLLERLTAQAVAAGAPLPAELPDGITPR
EAEVLVLIADGLSNVEIARTLHISRATVKTHINNLFSKSGARDRTGAVRYAYGRGLAHPPGTSVT

Nucleotide


Download         Length: 678 bp        

>NTDB_id=678142 OG428_RS26705 WP_147984069.1 5786193..5786870(+) (vraR) [Streptomyces sp. NBC_01422]
GTGAGCGCGCGGGTCGTGGTGGCGGACGACCAGTCGGTGGTGCGGGAGGGCATCGTCATGCTGCTCGGCCTGCTGCCCGG
CATCGAGGTGGTCGGGGCCGCGAAGGACGGGGACGAGGCGGTCGCCCTCGTCGCCGAGATGTCTCCCGACGTGGTCCTGA
TGGATCTGCGGATGCCCCGGTGCGACGGCGTCGAGGCCACGCGCCGTATCCGCAGGGAGCATCCCGGCACCCAGGTGGTG
GTCCTCACCACCTTCGCGGACGACGATTCCCTGTTCACCGCCCTGCAGGCGGGAGCGCGTGGCTACCTCACCAAGGACGC
CCGCGGCGAGGAGATCGCCCAGGCCATCCAGGCGGTGCTCTCCGGGGAGGCCGGGCTCTCACCGAAGGTGCAGAGCCGGC
TGCTGGAGCGGCTCACCGCCCAGGCCGTCGCGGCCGGGGCGCCGCTCCCGGCGGAGCTGCCCGACGGGATCACCCCCAGG
GAGGCCGAGGTGCTGGTCCTCATCGCGGACGGACTGTCCAACGTGGAGATCGCCCGCACGCTGCACATCTCCCGGGCCAC
GGTGAAGACGCACATCAACAACCTCTTCTCCAAGTCGGGCGCCCGTGACAGGACGGGAGCAGTGCGTTATGCCTACGGCC
GGGGTCTCGCACACCCACCCGGCACTTCCGTCACCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(157-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.741

96

0.391
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

99.556

0.378