Detailed information NTG0067748

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAMI_RS14155
• Genome accession: NZ_AP017320
• Coordinates: 2758574..2759461 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain MI
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2753574..2764461

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAMI_RS14120	-	2753593..2753685 (+)	93	WP_010956583.1	hypothetical protein	-
SAMI_RS14125 (SAMI_2593)	-	2753793..2754290 (-)	498	WP_001065268.1	glutathione peroxidase	-
SAMI_RS14130	-	2754300..2754560 (-)	261	WP_001791974.1	hypothetical protein	-
SAMI_RS14135	-	2754942..2755055 (-)	114	Protein_2697	hypothetical protein	-
SAMI_RS14145 (SAMI_2594)	-	2755714..2757714 (-)	2001	WP_000776751.1	ABC transporter permease	-
SAMI_RS14150 (SAMI_2595)	-	2757711..2758466 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAMI_RS14155 (SAMI_2596)	braS	2758574..2759461 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAMI_RS14160 (SAMI_2597)	braR	2759472..2760137 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAMI_RS14165 (SAMI_2598)	-	2760163..2760363 (-)	201	WP_000604730.1	hypothetical protein	-
SAMI_RS14175 (SAMI_2599)	-	2760561..2761985 (+)	1425	WP_000953755.1	alkaline phosphatase	-
SAMI_RS16045	-	2762045..2762146 (-)	102	WP_000731976.1	SE2200 family small protein	-
SAMI_RS14180 (SAMI_2600)	-	2762268..2762723 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAMI_RS14185 (SAMI_2601)	-	2762968..2763729 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=67748 SAMI_RS14155 WP_000143425.1 2758574..2759461(-) (braS) [Staphylococcus aureus strain MI]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=67748 SAMI_RS14155 WP_000143425.1 2758574..2759461(-) (braS) [Staphylococcus aureus strain MI]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1