Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   SAMI_RS08505 Genome accession   NZ_AP017320
Coordinates   1702669..1703355 (-) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain MI     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1697669..1708355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAMI_RS08485 (SAMI_1586) rpsT 1698583..1698834 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  SAMI_RS08490 (SAMI_1587) holA 1698879..1699853 (-) 975 WP_001282563.1 DNA polymerase III subunit delta -
  SAMI_RS08495 (SAMI_1588) comEC 1699910..1702111 (-) 2202 WP_001557362.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SAMI_RS08500 (SAMI_1589) - 1702116..1702577 (-) 462 WP_000439693.1 ComE operon protein 2 -
  SAMI_RS08505 (SAMI_1590) comEA 1702669..1703355 (-) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  SAMI_RS08510 (SAMI_1591) - 1703395..1704111 (-) 717 WP_000084830.1 class I SAM-dependent DNA methyltransferase -
  SAMI_RS08515 (SAMI_1592) rsfS 1704114..1704467 (-) 354 WP_001088020.1 ribosome silencing factor -
  SAMI_RS08520 (SAMI_1593) yqeK 1704468..1705052 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  SAMI_RS08525 (SAMI_1594) nadD 1705042..1705611 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  SAMI_RS08530 (SAMI_1595) yhbY 1705614..1705904 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  SAMI_RS08535 (SAMI_1596) aroE 1705908..1706714 (-) 807 WP_000666757.1 shikimate dehydrogenase -
  SAMI_RS08540 (SAMI_1597) yqeH 1706728..1707828 (-) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=67733 SAMI_RS08505 WP_001802022.1 1702669..1703355(-) (comEA) [Staphylococcus aureus strain MI]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=67733 SAMI_RS08505 WP_001802022.1 1702669..1703355(-) (comEA) [Staphylococcus aureus strain MI]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974

Multiple sequence alignment