Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   MU520_RS02190 Genome accession   NZ_CP095463
Coordinates   476037..476726 (+) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain TJS56     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 471037..481726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MU520_RS02165 - 471366..472709 (+) 1344 WP_012027650.1 DEAD/DEAH box helicase -
  MU520_RS02170 - 472727..472951 (+) 225 WP_002936682.1 DUF4059 family protein -
  MU520_RS02175 trxB 472965..473882 (+) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  MU520_RS02180 - 473892..474431 (+) 540 WP_012027649.1 DUF177 domain-containing protein -
  MU520_RS02185 gndA 474528..475955 (+) 1428 WP_012028448.1 NADP-dependent phosphogluconate dehydrogenase -
  MU520_RS02190 covR 476037..476726 (+) 690 WP_012027645.1 winged helix-turn-helix domain-containing protein Regulator
  MU520_RS02195 - 476816..477946 (+) 1131 WP_012027644.1 AI-2E family transporter -
  MU520_RS02200 nrdR 478018..478509 (+) 492 WP_002938341.1 transcriptional regulator NrdR -
  MU520_RS02205 - 478496..479647 (+) 1152 WP_012027643.1 replication initiation/membrane attachment protein -
  MU520_RS02210 dnaI 479647..480546 (+) 900 WP_012027642.1 primosomal protein DnaI -
  MU520_RS02215 - 480543..481255 (+) 713 Protein_435 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=676995 MU520_RS02190 WP_012027645.1 476037..476726(+) (covR) [Streptococcus suis strain TJS56]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=676995 MU520_RS02190 WP_012027645.1 476037..476726(+) (covR) [Streptococcus suis strain TJS56]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAAAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTGGTGAAGCCCTTTGTCAT
TAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGACTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGCTGGCAACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432