Detailed information NTG0676010

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG329_RS16695
• Genome accession: NZ_CP109422
• Coordinates: 3831042..3832175 (+)
• Length: 377 a.a.
• NCBI ID: WP_078075735.1
• Uniprot ID: A0A1U9QSN1
• Organism: Streptomyces sp. NBC_01506
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3826042..3837175

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG329_RS16680 (OG329_16635)	-	3826709..3827572 (+)	864	WP_405795978.1	hypothetical protein	-
OG329_RS16685 (OG329_16640)	-	3827598..3829415 (-)	1818	WP_405795980.1	BACON domain-containing protein	-
OG329_RS16690 (OG329_16645)	radA/sms	3829585..3830997 (+)	1413	WP_405795981.1	DNA repair protein RadA	Machinery gene
OG329_RS16695 (OG329_16650)	disA	3831042..3832175 (+)	1134	WP_078075735.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG329_RS16700 (OG329_16655)	-	3832272..3833114 (-)	843	WP_405795983.1	hypothetical protein	-
OG329_RS16705 (OG329_16660)	-	3833296..3834054 (+)	759	WP_405795984.1	phosphatase PAP2 family protein	-
OG329_RS16710 (OG329_16665)	-	3834221..3835132 (+)	912	WP_405795985.1	A/G-specific adenine glycosylase	-
OG329_RS16715 (OG329_16670)	-	3835451..3836071 (+)	621	WP_405795986.1	SigE family RNA polymerase sigma factor	-
OG329_RS16720 (OG329_16675)	-	3836059..3836760 (+)	702	WP_405795988.1	hypothetical protein	-

Sequence

Protein

• Length: 377 a.a.
• Molecular weight: 40512.47 Da
• Isoelectric Point: 4.9406

>NTDB_id=676010 OG329_RS16695 WP_078075735.1 3831042..3832175(+) (disA) [Streptomyces sp. NBC_01506]
MAANDRAAAPGKSGGGSGGSGTEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDKTVETMCTGGFVLDVEFTAT
RLRELCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCGFPVISVSQSMRLIALYVDGERRVLEE
SAAILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVSQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDE
LIAGVEPERELVVRDYVPEPTAKRSRTVAEAMTELDALSHTELLELPVVARALGYSGSPETLDSAVSPRGYRLLAKVPRL
PGAIIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1134 bp

>NTDB_id=676010 OG329_RS16695 WP_078075735.1 3831042..3832175(+) (disA) [Streptomyces sp. NBC_01506]
GTGGCAGCCAACGACCGGGCAGCAGCACCCGGAAAGTCCGGTGGTGGCTCCGGTGGATCCGGCACCGAAGCGCTGATGCG
CGCCTCACTGAGCGCCGTGGCGCCCGGCATGGCGCTGCGTGACGGGCTGGAGCGGATCCTCCGGGGGAACACCGGCGGTC
TCATCGTCCTGGGCATGGACAAGACCGTCGAGACGATGTGCACGGGCGGCTTCGTGCTGGACGTGGAATTCACCGCGACG
AGGCTCCGCGAGCTGTGCAAGCTCGACGGCGCGCTCATCCTCGACAAAGACATCACCAAAATTCTGCGGGCCGGTGTCCA
GCTCGTCCCCGACGCCTCCATCCCGACCGAGGAGACGGGCACCCGCCACCGCACGGCGGACCGGGTTTCCAAGCAGTGCG
GCTTCCCGGTCATCTCCGTGTCGCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGCCGGGTCCTGGAGGAG
TCGGCGGCGATCCTGTCGCGCGCCAACCAGGCCCTGGCGACGCTGGAGCGGTACAAGCTCCGGCTGGACGAGGTCGCCGG
CACGCTCTCCGCGCTGGAGATCGAGGACCTGGTGACGGTCCGCGACGTGACAGCGGTCTCGCAGCGCCTGGAGATGGTGC
GCCGGATCGCCACGGAAATCGCGGAGTACGTGGTCGAGTTGGGCACCGACGGGCGCCTTCTCTCCCTCCAGTTGGACGAG
TTGATCGCGGGCGTCGAGCCCGAGCGCGAGCTGGTCGTACGCGACTATGTGCCCGAGCCGACGGCGAAGCGCTCCCGTAC
GGTCGCCGAGGCGATGACCGAGCTGGACGCGCTCTCCCACACCGAGCTGCTGGAACTGCCGGTCGTGGCACGCGCGTTGG
GCTACAGCGGCTCGCCCGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGTTACCGGCTGCTGGCCAAGGTGCCGCGCCTG
CCGGGGGCCATCATCGAGCGGCTGGTCGAGCACTTCGGCGGCCTCCAGAAGCTGCTGGCGGCGAGCGTGGACGACCTCCA
GACGGTGGACGGGGTGGGCGAGGCGCGGGCGCGCAGCGTGCGCGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGG
AGCGGTACGTCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (158-300)

• Helix-hairpin-helix motif (HHH_2) (327-362)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (41-154)

3D structure

• AlphaFold DB: A0A1U9QSN1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.938	94.695	0.435