Detailed information NTG0675845

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: MUY23_RS08045
• Genome accession: NZ_CP095162
• Coordinates: 1634932..1636281 (-)
• Length: 449 a.a.
• NCBI ID: WP_002935841.1
• Uniprot ID: G7SGQ2
• Organism: Streptococcus suis strain TJS75
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1629932..1641281

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUY23_RS08030	-	1631489..1631944 (-)	456	WP_002935846.1	ATP-binding cassette domain-containing protein	-
MUY23_RS08035	-	1632183..1633385 (+)	1203	WP_280635075.1	IS110-like element ISSsu7 family transposase	-
MUY23_RS08040	vicX	1634122..1634925 (-)	804	WP_002935843.1	MBL fold metallo-hydrolase	Regulator
MUY23_RS08045	micB	1634932..1636281 (-)	1350	WP_002935841.1	cell wall metabolism sensor histidine kinase VicK	Regulator
MUY23_RS08050	micA	1636274..1636978 (-)	705	WP_002935840.1	response regulator YycF	Regulator
MUY23_RS08055	-	1637172..1637933 (+)	762	WP_002935839.1	amino acid ABC transporter ATP-binding protein	-
MUY23_RS08060	-	1637944..1638783 (+)	840	WP_002935837.1	transporter substrate-binding domain-containing protein	-
MUY23_RS08065	-	1638798..1639496 (+)	699	WP_002935835.1	amino acid ABC transporter permease	-
MUY23_RS08070	-	1639511..1640170 (+)	660	WP_002935828.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51039.08 Da
• Isoelectric Point: 4.5202

>NTDB_id=675845 MUY23_RS08045 WP_002935841.1 1634932..1636281(-) (micB) [Streptococcus suis strain TJS75]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide

• Length: 1350 bp

>NTDB_id=675845 MUY23_RS08045 WP_002935841.1 1634932..1636281(-) (micB) [Streptococcus suis strain TJS75]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGATATGGCGAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACGTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCCTGGTTGTCGTCTTGCATGATATGACCGAGCAAGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTAT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
TTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCACGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGTAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• PAS fold (PAS) (96-199)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

3D structure

• AlphaFold DB: G7SGQ2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	70.183	97.105	0.682
vicK	Streptococcus mutans UA159	70.72	89.755	0.635