Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   MUY23_RS02070 Genome accession   NZ_CP095162
Coordinates   430103..430792 (+) Length   229 a.a.
NCBI ID   WP_002942700.1    Uniprot ID   A0A126UNE5
Organism   Streptococcus suis strain TJS75     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 425103..435792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUY23_RS02045 - 425432..426775 (+) 1344 WP_002936685.1 DEAD/DEAH box helicase -
  MUY23_RS02050 - 426793..427017 (+) 225 WP_002936682.1 DUF4059 family protein -
  MUY23_RS02055 trxB 427031..427948 (+) 918 WP_002936674.1 thioredoxin-disulfide reductase -
  MUY23_RS02060 - 427958..428497 (+) 540 WP_013730515.1 DUF177 domain-containing protein -
  MUY23_RS02065 gndA 428594..430021 (+) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  MUY23_RS02070 covR 430103..430792 (+) 690 WP_002942700.1 winged helix-turn-helix domain-containing protein Regulator
  MUY23_RS02075 - 430882..432012 (+) 1131 WP_013730514.1 AI-2E family transporter -
  MUY23_RS02080 nrdR 432084..432575 (+) 492 WP_002938341.1 transcriptional regulator NrdR -
  MUY23_RS02085 - 432562..433713 (+) 1152 WP_002938340.1 hypothetical protein -
  MUY23_RS02090 dnaI 433713..434612 (+) 900 WP_002938337.1 primosomal protein DnaI -
  MUY23_RS02095 - 434609..435322 (+) 714 WP_053866418.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26225.11 Da        Isoelectric Point: 5.3968

>NTDB_id=675824 MUY23_RS02070 WP_002942700.1 430103..430792(+) (covR) [Streptococcus suis strain TJS75]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=675824 MUY23_RS02070 WP_002942700.1 430103..430792(+) (covR) [Streptococcus suis strain TJS75]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UNE5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432