Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MUA87_RS04540 Genome accession   NZ_CP095100
Coordinates   1020359..1021075 (-) Length   238 a.a.
NCBI ID   WP_002481723.1    Uniprot ID   -
Organism   Staphylococcus simulans strain IVB6189     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1015359..1026075
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA87_RS04520 (MUA87_04525) - 1016504..1017145 (+) 642 WP_002481727.1 redox-sensing transcriptional repressor Rex -
  MUA87_RS04525 (MUA87_04530) - 1017196..1017420 (-) 225 WP_002481726.1 sulfurtransferase TusA family protein -
  MUA87_RS04530 (MUA87_04535) - 1017476..1018564 (-) 1089 WP_262551336.1 YeeE/YedE family protein -
  MUA87_RS04535 (MUA87_04540) - 1018800..1020284 (+) 1485 WP_262551337.1 glycoside hydrolase family 32 protein -
  MUA87_RS04540 (MUA87_04545) agrA 1020359..1021075 (-) 717 WP_002481723.1 quorum-sensing response regulator AgrA Regulator
  MUA87_RS12865 (MUA87_04550) agrC 1021078..1022379 (-) 1302 WP_070463420.1 quorum-sensing sensor histidine kinase AgrC -
  MUA87_RS04550 (MUA87_04555) agrD 1022419..1022556 (-) 138 WP_023015908.1 cyclic lactone autoinducer peptide AgrD -
  MUA87_RS04555 (MUA87_04560) - 1022556..1023134 (-) 579 WP_262551338.1 accessory gene regulator AgrB -
  MUA87_RS04560 (MUA87_04565) - 1023446..1023610 (+) 165 WP_158257062.1 delta-lysin family phenol-soluble modulin -
  MUA87_RS04565 (MUA87_04570) - 1023915..1024715 (-) 801 WP_105978620.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27762.55 Da        Isoelectric Point: 4.6392

>NTDB_id=675396 MUA87_RS04540 WP_002481723.1 1020359..1021075(-) (agrA) [Staphylococcus simulans strain IVB6189]
MKIIICEDDVQQREHIESIIENYIMIEEKPLEVALSTGDPYEVLEFAKATNEICCYFLDIQLDSDINGIKLGSELRNYDS
VGSIIFITSHSELTYLTFVYKVAAMDFIFKDDPSEMKSRIIDCIETALTRLQLLSKESSLETIELKRGSNSVYVNYDDVM
FFESSAKSHRLIAHLDNRQIEFYGNLKDLSQLDDRFFRCHNSYVINRNNIEEVISKEREVYFKNGEHCYISVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=675396 MUA87_RS04540 WP_002481723.1 1020359..1021075(-) (agrA) [Staphylococcus simulans strain IVB6189]
GTGAAGATTATTATATGCGAAGATGATGTACAACAGCGTGAACACATTGAATCCATCATTGAAAATTATATTATGATTGA
AGAAAAACCTTTAGAAGTGGCGCTCTCAACGGGTGATCCTTATGAGGTATTAGAATTCGCTAAAGCTACAAATGAGATTT
GTTGTTACTTCTTAGATATTCAGTTAGATTCTGATATTAACGGTATTAAGCTTGGCAGCGAACTTAGAAACTATGATTCT
GTCGGCAGTATTATCTTTATTACTAGCCACAGTGAACTCACTTATCTTACTTTCGTTTATAAAGTAGCAGCCATGGACTT
TATTTTTAAAGATGACCCTTCAGAAATGAAATCTCGAATTATTGATTGTATCGAAACTGCATTGACGAGACTACAGTTGC
TTTCAAAAGAATCTAGTCTCGAAACAATTGAGTTAAAACGTGGCAGTAACTCAGTCTATGTTAATTACGATGATGTTATG
TTCTTTGAATCCTCGGCAAAATCACATCGCTTAATTGCGCATTTAGACAATCGTCAAATCGAATTTTATGGCAACTTAAA
AGATTTAAGCCAATTAGATGACCGCTTCTTCCGTTGTCACAATAGTTACGTCATTAATCGTAATAACATCGAAGAAGTAA
TATCCAAAGAACGTGAGGTCTACTTTAAAAATGGTGAACACTGTTATATCTCAGTAAGAAATTTAAAGAAAATCTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

79.412

100

0.794