Detailed information NTG0674501

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG278_RS20275
• Genome accession: NZ_CP109337
• Coordinates: 4532635..4533759 (-)
• Length: 374 a.a.
• NCBI ID: WP_328329764.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00455
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4527635..4538759

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG278_RS20245 (OG278_20270)	cseB	4527641..4528339 (-)	699	WP_328329755.1	two-component system response regulator CseB	-
OG278_RS20250 (OG278_20275)	-	4528352..4528975 (-)	624	WP_328329757.1	hypothetical protein	-
OG278_RS20255 (OG278_20280)	-	4529092..4529643 (-)	552	WP_266854649.1	SigE family RNA polymerase sigma factor	-
OG278_RS20260 (OG278_20285)	-	4529819..4530874 (-)	1056	WP_328329760.1	A/G-specific adenine glycosylase	-
OG278_RS20265 (OG278_20290)	-	4530891..4531499 (-)	609	WP_328329762.1	phosphatase PAP2 family protein	-
OG278_RS20270 (OG278_20295)	-	4531683..4532531 (+)	849	WP_328335557.1	hypothetical protein	-
OG278_RS20275 (OG278_20300)	disA	4532635..4533759 (-)	1125	WP_328329764.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG278_RS20280 (OG278_20305)	radA/sms	4533816..4535213 (-)	1398	WP_328329767.1	DNA repair protein RadA	Machinery gene
OG278_RS20285 (OG278_20310)	-	4535396..4537102 (+)	1707	WP_328329769.1	hypothetical protein	-
OG278_RS20290 (OG278_20315)	-	4537166..4537996 (-)	831	WP_328329771.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40272.15 Da
• Isoelectric Point: 5.0132

>NTDB_id=674501 OG278_RS20275 WP_328329764.1 4532635..4533759(-) (disA) [Streptomyces sp. NBC_00455]
MAANDRAAPGRSGGSSSGNEALMRATLSAVAPGTALRDGLERILRGNTGGLIVLGMDKSVEAMCTGGFVMDVEFAATRLR
ELCKLDGALILDKDLTKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCGFPVVSVSQSMHLIALYVDGERRVLEESAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVTEALVDLNTLSHTELLELPVVARALGYSGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=674501 OG278_RS20275 WP_328329764.1 4532635..4533759(-) (disA) [Streptomyces sp. NBC_00455]
GTGGCAGCCAATGACCGAGCAGCACCCGGGAGATCCGGCGGGAGCTCGTCCGGCAATGAAGCGCTGATGCGTGCCACGCT
GAGCGCTGTCGCGCCCGGTACCGCGCTGCGCGACGGCCTGGAGCGGATCCTCCGCGGGAACACCGGCGGCCTCATCGTCC
TGGGCATGGACAAGAGCGTCGAAGCGATGTGCACCGGCGGTTTCGTCATGGACGTGGAGTTCGCCGCGACCCGCCTGCGG
GAGCTGTGCAAGCTCGACGGCGCGCTGATCCTCGACAAGGATCTGACCAAGATTCTCCGGGCCGGCGTCCAGCTGGTCCC
GGACGCGTCGATCCCCACCGAGGAGACCGGCACCCGCCACCGCACGGCGGACCGGGTCTCCAAGCAGTGCGGCTTCCCCG
TCGTCTCCGTATCGCAGTCGATGCACCTGATCGCGCTGTACGTGGACGGGGAGCGCCGGGTCCTGGAGGAGTCGGCGGCG
ATCCTGTCCCGCGCCAACCAGGCGCTGGCCACGCTGGAGCGGTACAAGCTCCGGCTGGACGAGGTGGCGGGCACGCTGTC
CGCGCTGGAGATCGAGGACCTGGTGACGGTCCGCGACGTGACGGCGGTCGCGCAGCGTCTTGAGATGGTCCGGCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACCGACGGCCGGCTGCTCTCCCTCCAGCTGGACGAGCTGATCGCC
GGGGTCGAGCCCGAGCGGGAGCTGGTGGTCAGAGACTATGTGCCGGAGCCGACGGCGAAGCGTTCGCGCACGGTCACCGA
GGCACTGGTCGACCTCAACACGCTCAGCCACACGGAGCTGCTCGAACTTCCCGTGGTGGCAAGGGCGTTGGGATACAGCG
GCTCCCCGGAGACGCTCGACTCGGCGGTGTCGCCGCGCGGGTACCGGCTGCTGGCCAAGGTGCCGAGGCTGCCCGGGGCG
ATCATCGAGCGGCTGGTCGAGCACTTCGGCGGGCTGCAGAAGCTGCTCGCTGCGAGCGTGGACGATCTGCAGGCGGTGGA
CGGGGTCGGGGAGGCGCGGGCCCGCAGCGTCCGGGAGGGGCTTTCGCGGCTCGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• Helix-hairpin-helix motif (HHH_2) (324-359)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.045	94.652	0.436