Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   MUO44_RS02520 Genome accession   NZ_CP094928
Coordinates   539037..539606 (+) Length   189 a.a.
NCBI ID   WP_000872877.1    Uniprot ID   A0A641A2F3
Organism   Staphylococcus aureus strain 8     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 534037..544606
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUO44_RS02495 (MUO44_02495) cysE 535250..535897 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  MUO44_RS02500 (MUO44_02500) cysS 535881..537281 (+) 1401 WP_000631973.1 cysteine--tRNA ligase -
  MUO44_RS02505 (MUO44_02505) - 537274..537678 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  MUO44_RS02510 (MUO44_02510) rlmB 537686..538432 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  MUO44_RS02515 (MUO44_02515) - 538432..538956 (+) 525 WP_000664738.1 NYN domain-containing protein -
  MUO44_RS02520 (MUO44_02520) sigH 539037..539606 (+) 570 WP_000872877.1 RNA polymerase sigma factor Regulator
  MUO44_RS02525 (MUO44_02525) rpmG 539721..539864 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  MUO44_RS02530 (MUO44_02530) secE 539920..540102 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  MUO44_RS02535 (MUO44_02535) nusG 540115..540663 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  MUO44_RS02540 (MUO44_02540) rplK 540844..541266 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  MUO44_RS02545 (MUO44_02545) rplA 541474..542166 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  MUO44_RS02550 (MUO44_02550) rplJ 542438..542938 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  MUO44_RS02555 (MUO44_02555) rplL 542981..543349 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  MUO44_RS02560 (MUO44_02560) - 543524..544132 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23126.01 Da        Isoelectric Point: 9.6015

>NTDB_id=674185 MUO44_RS02520 WP_000872877.1 539037..539606(+) (sigH) [Staphylococcus aureus strain 8]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSVFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=674185 MUO44_RS02520 WP_000872877.1 539037..539606(+) (sigH) [Staphylococcus aureus strain 8]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGTATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641A2F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

100

100

1
  sigH Staphylococcus aureus N315

97.884

100

0.979