Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   MUO48_RS12045 Genome accession   NZ_CP094925
Coordinates   2414206..2414775 (+) Length   189 a.a.
NCBI ID   WP_000872874.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 15     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2409206..2419775
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUO48_RS12020 (MUO48_12010) cysE 2410419..2411066 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  MUO48_RS12025 (MUO48_12015) cysS 2411050..2412450 (+) 1401 WP_000631974.1 cysteine--tRNA ligase -
  MUO48_RS12030 (MUO48_12020) - 2412443..2412847 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  MUO48_RS12035 (MUO48_12025) rlmB 2412855..2413601 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  MUO48_RS12040 (MUO48_12030) - 2413601..2414125 (+) 525 WP_000664738.1 NYN domain-containing protein -
  MUO48_RS12045 (MUO48_12035) sigH 2414206..2414775 (+) 570 WP_000872874.1 RNA polymerase sigma factor Regulator
  MUO48_RS12050 (MUO48_12040) rpmG 2414890..2415033 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  MUO48_RS12055 (MUO48_12045) secE 2415089..2415271 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  MUO48_RS12060 (MUO48_12050) nusG 2415284..2415832 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  MUO48_RS12065 (MUO48_12055) rplK 2416013..2416435 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  MUO48_RS12070 (MUO48_12060) rplA 2416643..2417335 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  MUO48_RS12075 (MUO48_12065) rplJ 2417608..2418108 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  MUO48_RS12080 (MUO48_12070) rplL 2418151..2418519 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  MUO48_RS12085 (MUO48_12075) - 2418694..2419302 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23043.97 Da        Isoelectric Point: 9.6030

>NTDB_id=674090 MUO48_RS12045 WP_000872874.1 2414206..2414775(+) (sigH) [Staphylococcus aureus strain 15]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCKQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=674090 MUO48_RS12045 WP_000872874.1 2414206..2414775(+) (sigH) [Staphylococcus aureus strain 15]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTAAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCGATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

98.413

100

0.984
  sigH Staphylococcus aureus MW2

98.413

100

0.984