Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   MUB20_RS08770 Genome accession   NZ_CP094859
Coordinates   1864865..1865440 (-) Length   191 a.a.
NCBI ID   WP_001829272.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain C99     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1854526..1864359 1864865..1865440 flank 506


Gene organization within MGE regions


Location: 1854526..1865440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUB20_RS08660 (MUB20_08660) - 1854526..1855083 (-) 558 WP_001831688.1 GNAT family N-acetyltransferase -
  MUB20_RS08665 (MUB20_08665) - 1855314..1855529 (+) 216 WP_001831694.1 NINE protein -
  MUB20_RS08670 (MUB20_08670) - 1856070..1856600 (+) 531 WP_237625884.1 N-acetyltransferase -
  MUB20_RS08675 (MUB20_08675) - 1856836..1857033 (+) 198 WP_002456096.1 hypothetical protein -
  MUB20_RS08680 (MUB20_08680) - 1857374..1857607 (-) 234 Protein_1689 AAA family ATPase -
  MUB20_RS08685 (MUB20_08685) - 1857937..1858305 (+) 369 WP_230372882.1 hypothetical protein -
  MUB20_RS12090 - 1858288..1858422 (-) 135 WP_002439268.1 hypothetical protein -
  MUB20_RS08690 (MUB20_08690) - 1858436..1858648 (-) 213 Protein_1692 DUF771 domain-containing protein -
  MUB20_RS08695 (MUB20_08695) - 1858652..1859416 (-) 765 WP_237625885.1 phage regulatory protein/antirepressor Ant -
  MUB20_RS08700 (MUB20_08700) - 1859466..1859672 (+) 207 WP_002439266.1 hypothetical protein -
  MUB20_RS08705 (MUB20_08705) - 1859661..1859825 (-) 165 WP_002439265.1 hypothetical protein -
  MUB20_RS08710 (MUB20_08710) - 1859822..1860076 (-) 255 WP_237625886.1 helix-turn-helix transcriptional regulator -
  MUB20_RS08715 (MUB20_08715) - 1860270..1860599 (+) 330 WP_002439260.1 helix-turn-helix transcriptional regulator -
  MUB20_RS08720 (MUB20_08720) - 1860611..1861072 (+) 462 WP_002469232.1 ImmA/IrrE family metallo-endopeptidase -
  MUB20_RS08725 (MUB20_08725) - 1861088..1861606 (+) 519 WP_002439256.1 hypothetical protein -
  MUB20_RS08730 (MUB20_08730) - 1861608..1862051 (+) 444 WP_237625888.1 hypothetical protein -
  MUB20_RS08735 (MUB20_08735) - 1862124..1862318 (+) 195 WP_002439253.1 hypothetical protein -
  MUB20_RS08740 (MUB20_08740) - 1862387..1862902 (+) 516 WP_002439252.1 hypothetical protein -
  MUB20_RS08745 (MUB20_08745) - 1862904..1863239 (+) 336 WP_002439251.1 hypothetical protein -
  MUB20_RS08750 (MUB20_08750) - 1863295..1863693 (+) 399 Protein_1704 phage integrase SAM-like domain-containing protein -
  MUB20_RS08755 (MUB20_08755) - 1863799..1864359 (+) 561 WP_279594400.1 site-specific integrase -
  MUB20_RS08770 (MUB20_08770) comK/comK1 1864865..1865440 (-) 576 WP_001829272.1 competence protein ComK Regulator

Sequence

Protein


Download         Length: 191 a.a.        Molecular weight: 22782.87 Da        Isoelectric Point: 9.2887

>NTDB_id=673770 MUB20_RS08770 WP_001829272.1 1864865..1865440(-) (comK/comK1) [Staphylococcus epidermidis strain C99]
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN

Nucleotide


Download         Length: 576 bp        

>NTDB_id=673770 MUB20_RS08770 WP_001829272.1 1864865..1865440(-) (comK/comK1) [Staphylococcus epidermidis strain C99]
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG

Domains

Predicted by InterproScan.

ComK protein (ComK)

(7-158)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

76.757

96.859

0.743
  comK/comK1 Staphylococcus aureus N315

76.757

96.859

0.743