Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB03_RS22980 Genome accession   NZ_CP109266
Coordinates   5095571..5096233 (+) Length   220 a.a.
NCBI ID   WP_267003650.1    Uniprot ID   A0ABV2UEL0
Organism   Streptomyces sp. NBC_01643     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5090571..5101233
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB03_RS22960 (OHB03_22995) - 5091059..5091907 (+) 849 WP_326604967.1 tryptophan 2,3-dioxygenase family protein -
  OHB03_RS22965 (OHB03_23000) kynU 5091900..5093138 (+) 1239 WP_355223549.1 kynureninase -
  OHB03_RS22970 (OHB03_23005) - 5093248..5094123 (+) 876 WP_326814762.1 alpha/beta hydrolase -
  OHB03_RS22975 (OHB03_23010) - 5094255..5095574 (+) 1320 WP_355223550.1 histidine kinase -
  OHB03_RS22980 (OHB03_23015) vraR 5095571..5096233 (+) 663 WP_267003650.1 response regulator transcription factor Regulator
  OHB03_RS22985 (OHB03_23020) - 5096271..5097500 (+) 1230 WP_355223551.1 cytochrome P450 -
  OHB03_RS22990 (OHB03_23025) - 5097641..5099242 (-) 1602 WP_406406677.1 ABC transporter permease -
  OHB03_RS22995 (OHB03_23030) - 5099239..5100162 (-) 924 WP_406406679.1 ATP-binding cassette domain-containing protein -
  OHB03_RS23000 (OHB03_23035) - 5100277..5100810 (+) 534 WP_389121196.1 GbsR/MarR family transcriptional regulator -
  OHB03_RS23005 (OHB03_23040) - 5100855..5101127 (-) 273 WP_267003640.1 DUF1876 domain-containing protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23521.32 Da        Isoelectric Point: 4.9350

>NTDB_id=672957 OHB03_RS22980 WP_267003650.1 5095571..5096233(+) (vraR) [Streptomyces sp. NBC_01643]
MNDIRVLIVDDQMMVREGFSVLLGAMPGIEVVGEAVDGRQAIAQAAALRPDVVLMDIRMPELNGIEATREIVANDAAAKV
LVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPTVTKRLITEFSRLAGAPRPPALARIGDLTER
ETEVLVLIAQGLSNAEIASHLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPA

Nucleotide


Download         Length: 663 bp        

>NTDB_id=672957 OHB03_RS22980 WP_267003650.1 5095571..5096233(+) (vraR) [Streptomyces sp. NBC_01643]
ATGAACGACATCCGTGTCCTGATCGTCGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTGCTCCTGGGGGCGATGCC
GGGCATCGAGGTCGTCGGCGAGGCCGTCGACGGCCGGCAGGCCATCGCCCAGGCGGCCGCGCTGCGGCCCGACGTGGTGC
TGATGGACATCCGGATGCCGGAGCTCAACGGCATCGAGGCGACCCGTGAGATCGTCGCGAACGACGCGGCCGCCAAGGTG
CTCGTGCTGACCACGTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCCGGGGCGTCCGGGTTTCTGCTGAAGGA
CGCCTCCGCCCGCCAGCTCGCCGACGGGGTACGGGTGGTGGCGGCCGGGGAGGCGCTGCTGGCGCCGACCGTCACGAAGC
GGCTGATCACCGAGTTCTCCCGGCTCGCGGGGGCCCCGCGGCCGCCCGCGCTCGCCCGGATCGGCGATCTGACGGAGCGC
GAGACGGAGGTGCTCGTACTCATCGCGCAGGGCCTGTCGAACGCGGAGATCGCCTCGCACCTGGTGGTCGCCGAGTCCAC
CATCAAGACGCATGTGAGCCGCATCCTGGTGAAGCTGGGGCTGCGGGACCGTACGCAGGCGGCGGTGTTCGCGTACGAGG
CGCGGCTGGTCACCCCGGCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-115)

Bacterial regulatory proteins, luxR family (GerE)

(157-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.86

97.273

0.436
  degU Bacillus subtilis subsp. subtilis str. 168

42.727

100

0.427