Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   MUA25_RS04975 Genome accession   NZ_CP094801
Coordinates   1023707..1024276 (-) Length   189 a.a.
NCBI ID   WP_000287265.1    Uniprot ID   A0A7U7EXU5
Organism   Staphylococcus aureus strain IVB6155     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1018707..1029276
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA25_RS04955 (MUA25_04950) - 1020210..1021568 (+) 1359 WP_045179025.1 TrkH family potassium uptake protein -
  MUA25_RS04960 (MUA25_04955) - 1021707..1023218 (+) 1512 WP_045179022.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -
  MUA25_RS04975 (MUA25_04970) comK/comK1 1023707..1024276 (-) 570 WP_000287265.1 competence protein ComK Regulator
  MUA25_RS04980 (MUA25_04975) - 1024486..1024704 (+) 219 WP_045179020.1 IDEAL domain-containing protein -
  MUA25_RS04985 (MUA25_04980) - 1024785..1025771 (-) 987 WP_000668820.1 lipoate--protein ligase -
  MUA25_RS04990 (MUA25_04985) - 1025970..1026146 (+) 177 WP_000214898.1 YkvS family protein -
  MUA25_RS04995 (MUA25_04990) - 1026161..1026763 (+) 603 WP_001033867.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  MUA25_RS14525 - 1027079..1027141 (+) 63 WP_240785570.1 putative holin-like toxin -
  MUA25_RS05000 (MUA25_04995) - 1027680..1027781 (+) 102 WP_001790623.1 hypothetical protein -
  MUA25_RS05005 (MUA25_05000) - 1027791..1028063 (+) 273 WP_001794574.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22601.83 Da        Isoelectric Point: 9.6091

>NTDB_id=672870 MUA25_RS04975 WP_000287265.1 1023707..1024276(-) (comK/comK1) [Staphylococcus aureus strain IVB6155]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=672870 MUA25_RS04975 WP_000287265.1 1023707..1024276(-) (comK/comK1) [Staphylococcus aureus strain IVB6155]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
TGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCACCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXU5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

100

100

1
  comK/comK1 Staphylococcus aureus N315

100

100

1