Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG939_RS11250 Genome accession   NZ_CP109209
Coordinates   2548010..2548660 (+) Length   216 a.a.
NCBI ID   WP_329168835.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01685     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2543010..2553660
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG939_RS11220 (OG939_11185) - 2543257..2543898 (-) 642 WP_124274708.1 TetR/AcrR family transcriptional regulator -
  OG939_RS11225 (OG939_11190) - 2543981..2544763 (+) 783 WP_124274707.1 ATP-binding cassette domain-containing protein -
  OG939_RS11230 (OG939_11195) - 2544771..2545520 (+) 750 WP_319222886.1 ABC transporter permease -
  OG939_RS11235 (OG939_11200) - 2545534..2546106 (+) 573 WP_124274705.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
  OG939_RS11240 (OG939_11205) - 2546108..2546665 (-) 558 WP_124274704.1 hypothetical protein -
  OG939_RS11245 (OG939_11210) - 2546817..2548013 (+) 1197 WP_329168833.1 histidine kinase -
  OG939_RS11250 (OG939_11215) vraR 2548010..2548660 (+) 651 WP_329168835.1 response regulator transcription factor Regulator
  OG939_RS11255 (OG939_11220) - 2548821..2550704 (+) 1884 WP_147983860.1 glycoside hydrolase family 18 chitinase -
  OG939_RS11260 (OG939_11225) - 2550846..2551292 (-) 447 WP_014154045.1 DUF2550 domain-containing protein -
  OG939_RS11265 (OG939_11230) - 2551435..2551809 (-) 375 WP_099174454.1 F0F1 ATP synthase subunit epsilon -
  OG939_RS11270 (OG939_11235) atpD 2551919..2553361 (-) 1443 WP_099174455.1 F0F1 ATP synthase subunit beta -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 22948.41 Da        Isoelectric Point: 4.7633

>NTDB_id=672697 OG939_RS11250 WP_329168835.1 2548010..2548660(+) (vraR) [Streptomyces sp. NBC_01685]
MTIRVLVAEDQSAVRAGLVLILGSAPDIEVVGEAADGEAAVRLARELRPDLVLMDVQMPRLDGVSATRQVVAERLADVLV
LTTFDLDEYVFGALRAGASGFLLKNTEAGDLIDAVRTVARGEGMIAPAVTRRLIEEFAGSTAPRRADGPGREALDALTRR
EREVLGCLGEGLSNAEIAGRLQMAEATVKTHVSRLLGKLELRSRAQAAVLAQELGL

Nucleotide


Download         Length: 651 bp        

>NTDB_id=672697 OG939_RS11250 WP_329168835.1 2548010..2548660(+) (vraR) [Streptomyces sp. NBC_01685]
ATGACGATCCGGGTACTGGTCGCCGAGGACCAGTCGGCGGTGCGCGCGGGGCTGGTGCTGATCCTGGGCAGCGCGCCGGA
CATCGAGGTCGTGGGCGAGGCGGCCGACGGCGAGGCCGCCGTGCGCCTGGCGCGTGAACTGCGCCCGGATCTGGTGCTGA
TGGACGTACAGATGCCCCGGCTCGACGGGGTGTCCGCGACCCGGCAGGTGGTGGCGGAGCGGCTGGCGGACGTGCTGGTG
CTGACCACCTTCGACCTGGACGAGTACGTCTTCGGCGCACTGCGGGCGGGCGCGTCGGGCTTCCTGCTGAAGAACACCGA
GGCCGGCGACCTGATCGACGCGGTACGCACGGTGGCGCGCGGCGAGGGCATGATCGCCCCCGCCGTCACCCGCCGGCTGA
TCGAGGAGTTCGCCGGGAGCACCGCCCCGCGCAGGGCGGACGGGCCGGGCCGCGAGGCCCTGGACGCGCTGACCCGGCGG
GAGCGGGAGGTCCTGGGCTGCCTCGGCGAGGGGCTGTCGAACGCGGAGATCGCCGGGCGTCTCCAGATGGCGGAGGCCAC
GGTGAAGACCCATGTCAGCAGGCTCCTGGGAAAGCTGGAGCTGCGCAGCAGGGCCCAAGCGGCGGTGCTGGCTCAGGAGT
TGGGCCTCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-211)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.396

100

0.426
  degU Bacillus subtilis subsp. subtilis str. 168

40.09

100

0.412