Detailed information NTG0672691

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA93_RS09810
• Genome accession: NZ_CP094793
• Coordinates: 1997221..1998264 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain IVB6165
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1992221..2003264

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA93_RS09780 (MUA93_09770)	-	1992642..1993898 (-)	1257	WP_001793428.1	aminopeptidase	-
MUA93_RS09785 (MUA93_09775)	-	1993901..1994101 (-)	201	WP_000180460.1	DUF1128 family protein	-
MUA93_RS09790 (MUA93_09780)	-	1994248..1994712 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
MUA93_RS09795 (MUA93_09785)	-	1994719..1994994 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
MUA93_RS09800 (MUA93_09790)	-	1995272..1996489 (+)	1218	WP_045158466.1	YihY/virulence factor BrkB family protein	-
MUA93_RS09805 (MUA93_09795)	vraR	1996602..1997231 (-)	630	WP_262541884.1	two-component system response regulator VraR	Regulator
MUA93_RS09810 (MUA93_09800)	vraS	1997221..1998264 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
MUA93_RS09815 (MUA93_09805)	liaF	1998261..1998962 (-)	702	WP_000149068.1	cell wall-active antibiotics response protein LiaF	-
MUA93_RS09820 (MUA93_09810)	-	1998977..1999363 (-)	387	WP_001110179.1	hypothetical protein	-
MUA93_RS09825 (MUA93_09815)	map	1999580..2000338 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
MUA93_RS09830 (MUA93_09820)	-	2000865..2001851 (+)	987	WP_000999713.1	FUSC family protein	-
MUA93_RS09835 (MUA93_09825)	-	2002040..2002453 (-)	414	WP_252550078.1	hypothetical protein	-
MUA93_RS09840 (MUA93_09830)	-	2002482..2002592 (-)	111	WP_262542999.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=672691 MUA93_RS09810 WP_001017131.1 1997221..1998264(-) (vraS) [Staphylococcus aureus strain IVB6165]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=672691 MUA93_RS09810 WP_001017131.1 1997221..1998264(-) (vraS) [Staphylococcus aureus strain IVB6165]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTACTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTGCAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1