Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SITYG_RS07665 Genome accession   NZ_AP014880
Coordinates   1510151..1510840 (-) Length   229 a.a.
NCBI ID   WP_003071837.1    Uniprot ID   A0A3R9LG80
Organism   Streptococcus intermedius strain TYG1620     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1505151..1515840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS07645 (SITYG_15180) - 1505634..1506116 (+) 483 WP_096363075.1 streptodornase -
  SITYG_RS07650 (SITYG_15190) - 1506167..1506982 (-) 816 WP_009569215.1 endonuclease/exonuclease/phosphatase family protein -
  SITYG_RS07655 (SITYG_15200) - 1507000..1509189 (-) 2190 WP_096363076.1 PTS transporter subunit IIBC -
  SITYG_RS07660 (SITYG_15210) - 1509401..1509850 (-) 450 Protein_1487 PTS glucose transporter subunit IIA -
  SITYG_RS07665 (SITYG_15220) covR 1510151..1510840 (-) 690 WP_003071837.1 DNA-binding response regulator Regulator
  SITYG_RS07670 (SITYG_15230) gndA 1510849..1512273 (-) 1425 WP_096363078.1 NADP-dependent phosphogluconate dehydrogenase -
  SITYG_RS07675 (SITYG_15240) - 1512365..1512901 (-) 537 WP_096363079.1 DUF177 domain-containing protein -
  SITYG_RS07680 (SITYG_15250) - 1513094..1514320 (+) 1227 WP_096363080.1 transporter -
  SITYG_RS07685 (SITYG_15260) htpX 1514423..1515319 (-) 897 WP_096363081.1 zinc metalloprotease HtpX -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26549.61 Da        Isoelectric Point: 6.5002

>NTDB_id=67267 SITYG_RS07665 WP_003071837.1 1510151..1510840(-) (covR) [Streptococcus intermedius strain TYG1620]
MGKRILLVENEKKLAQFISLELQNEGYRVDLFETGKDALTSARANQYDLFLLNFMLEDMTGTEFAEQLSLIKPASVIIVL
DNRDIILKYTEEIQRFAVSYMIEPFIVMDLVGKISAIFRGRDFIDHHCSQMKVSTSYRNLRIDVQNHTVYRGNEIISLTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKLDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=67267 SITYG_RS07665 WP_003071837.1 1510151..1510840(-) (covR) [Streptococcus intermedius strain TYG1620]
ATGGGGAAGCGGATTTTATTAGTTGAGAATGAAAAAAAATTAGCACAATTTATTAGCTTAGAGTTGCAAAATGAAGGTTA
TCGAGTGGATCTTTTTGAAACGGGAAAAGATGCTTTAACATCTGCGAGAGCTAATCAATACGATTTATTCCTGTTAAATT
TTATGCTTGAAGATATGACAGGAACGGAGTTTGCTGAGCAATTGAGTTTGATAAAGCCTGCTTCAGTCATTATTGTATTG
GATAATCGTGATATTATTTTAAAATATACTGAGGAAATCCAACGTTTTGCTGTTAGTTATATGATAGAGCCTTTCATTGT
GATGGACTTGGTCGGAAAAATTTCTGCTATTTTTCGTGGGCGTGATTTTATTGATCATCATTGTAGTCAGATGAAAGTTT
CAACATCTTATCGGAATCTTCGCATTGACGTGCAAAATCATACTGTATATCGAGGGAATGAAATAATTTCTTTGACTAGA
AGAGAGTATGATTTGTTAGCAACGCTGATGGGCAGTCATCAGGCTTTAAGTCGTGAACAGCTGTTAGAGCGCGTTTGGAA
ATACGAAGGAGCTGTTGAGACAAATGTTGTTGATGTCTATATTCGTTATCTTCGTAGTAAACTTGATATAGCAGGGCAGA
AAAGTTACATCAAAACTGTGCGTGGTGTTGGCTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-227)

Response regulator receiver domain (Response_reg)

(5-82)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9LG80

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.175

99.563

0.45

Multiple sequence alignment