Detailed information NTG0067250

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: SITYG_RS03215
• Genome accession: NZ_AP014880
• Coordinates: 620290..621036 (-)
• Length: 248 a.a.
• NCBI ID: WP_041787711.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain TYG1620
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 615290..626036

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SITYG_RS03200 (SITYG_06150)	-	617320..618681 (+)	1362	WP_096362644.1	bacteriocin secretion accessory protein	-
SITYG_RS03205 (SITYG_06160)	-	618778..618927 (+)	150	WP_096362645.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
SITYG_RS10535 (SITYG_06170)	-	618972..619595 (-)	624	WP_231870255.1	sensor histidine kinase	-
SITYG_RS10540 (SITYG_06180)	-	619617..620288 (-)	672	WP_231870256.1	hypothetical protein	-
SITYG_RS03215 (SITYG_06190)	comE/blpR	620290..621036 (-)	747	WP_041787711.1	response regulator transcription factor	Regulator
SITYG_RS03220 (SITYG_06200)	-	621205..621918 (-)	714	WP_096362646.1	CPBP family intramembrane glutamic endopeptidase	-
SITYG_RS03225 (SITYG_06210)	-	622150..622374 (+)	225	WP_003025424.1	Blp family class II bacteriocin	-
SITYG_RS03230 (SITYG_06220)	-	622462..622782 (+)	321	WP_003037422.1	hypothetical protein	-
SITYG_RS03235 (SITYG_06230)	-	622790..623011 (+)	222	WP_003025422.1	Blp family class II bacteriocin	-
SITYG_RS03240 (SITYG_06240)	-	623252..623479 (+)	228	WP_096362647.1	bacteriocin class II family protein	-
SITYG_RS03245 (SITYG_06250)	-	623515..623835 (+)	321	WP_096362648.1	hypothetical protein	-
SITYG_RS03250 (SITYG_06260)	-	624065..624280 (+)	216	WP_009568291.1	bacteriocin class II family protein	-
SITYG_RS03255 (SITYG_06270)	-	624509..624802 (+)	294	WP_004233800.1	bacteriocin immunity protein	-
SITYG_RS03260 (SITYG_06280)	-	624970..625221 (+)	252	WP_020998893.1	hypothetical protein	-
SITYG_RS03265 (SITYG_06290)	-	625432..625662 (+)	231	WP_096363326.1	bacteriocin class II family protein	-

Sequence

Protein

• Length: 248 a.a.
• Molecular weight: 28755.16 Da
• Isoelectric Point: 7.3918

>NTDB_id=67250 SITYG_RS03215 WP_041787711.1 620290..621036(-) (comE/blpR) [Streptococcus intermedius strain TYG1620]
MNIFILEDDLTQQYYMETIVEEIIEKHRLQYHHFEVFGKPKQLLEAISEKGSHQVFFLDIEIKTEEKKGLDVAKKIREID
PYAIIVFVTSHSELMPAAFKLQVGALDYLDKSLSKEALKKRIETALLHTENLTGKGLADDSLLFETPHTQIQVPFKDILY
IETSSRPHRLVLYTHRGRTEFTANLSDMLKKEKRFYQCHRSFVVNPANVHQVDKVNHILHFQNGATCLVSRSKIKGLTEA
IAALHWRE

Nucleotide

• Length: 747 bp

>NTDB_id=67250 SITYG_RS03215 WP_041787711.1 620290..621036(-) (comE/blpR) [Streptococcus intermedius strain TYG1620]
ATGAATATTTTTATTTTAGAAGATGATCTTACTCAACAATATTATATGGAGACTATTGTTGAAGAAATTATCGAAAAACA
TCGTCTTCAATATCACCATTTTGAAGTTTTTGGAAAACCTAAACAATTACTAGAAGCCATATCTGAGAAAGGAAGCCATC
AGGTTTTCTTTTTGGATATTGAAATCAAAACTGAAGAAAAAAAGGGCTTAGACGTCGCCAAAAAGATACGCGAGATAGAT
CCTTATGCCATTATTGTCTTTGTAACCAGTCACTCTGAATTGATGCCGGCAGCGTTTAAACTGCAAGTCGGCGCCCTTGA
CTATCTTGACAAATCGTTATCAAAAGAAGCTTTGAAAAAACGGATCGAAACTGCGCTGCTACATACTGAAAACCTAACAG
GCAAAGGCCTGGCAGACGATTCTCTTCTCTTTGAAACACCTCATACACAAATACAAGTGCCGTTTAAAGATATTCTTTAC
ATTGAAACTTCCTCTCGTCCTCACCGTTTAGTACTTTACACACATAGAGGGCGTACGGAATTTACTGCCAATCTTTCAGA
TATGTTAAAAAAAGAAAAACGGTTCTACCAATGTCATCGTTCCTTTGTTGTTAACCCAGCTAATGTCCATCAAGTGGATA
AAGTAAATCATATCCTTCACTTCCAGAATGGTGCTACTTGTCTTGTTTCTAGATCAAAAATAAAAGGGTTAACAGAAGCT
ATTGCAGCCCTGCACTGGAGGGAATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-123)

• LytTr DNA-binding domain (LytTR) (151-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	50.206	97.984	0.492
comE/comE1	Streptococcus equinus JB1	45.992	95.565	0.44