Detailed information NTG0067249

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SITYG_RS03195
• Genome accession: NZ_AP014880
• Coordinates: 615159..617309 (+)
• Length: 716 a.a.
• NCBI ID: WP_096362643.1
• Uniprot ID: A0AAD1C802
• Organism: Streptococcus intermedius strain TYG1620
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 610159..622309

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SITYG_RS03160 (SITYG_06080)	pyrH	610190..610930 (+)	741	WP_003069937.1	UMP kinase	-
SITYG_RS03165 (SITYG_06090)	frr	610934..611491 (+)	558	WP_003069936.1	ribosome recycling factor	-
SITYG_RS03170 (SITYG_06100)	cvfB	611604..612458 (+)	855	WP_096362639.1	RNA-binding virulence regulatory protein CvfB	-
SITYG_RS03175 (SITYG_06110)	holA	612518..613555 (+)	1038	WP_096362640.1	DNA polymerase III subunit delta	-
SITYG_RS03180 (SITYG_06120)	-	613626..614231 (+)	606	WP_096362641.1	superoxide dismutase	-
SITYG_RS03185 (SITYG_06130)	-	614304..614678 (-)	375	WP_003073369.1	hypothetical protein	-
SITYG_RS03195 (SITYG_06140)	comA/nlmT	615159..617309 (+)	2151	WP_096362643.1	peptide cleavage/export ABC transporter	Regulator
SITYG_RS03200 (SITYG_06150)	-	617320..618681 (+)	1362	WP_096362644.1	bacteriocin secretion accessory protein	-
SITYG_RS03205 (SITYG_06160)	-	618778..618927 (+)	150	WP_096362645.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
SITYG_RS10535 (SITYG_06170)	-	618972..619595 (-)	624	WP_231870255.1	sensor histidine kinase	-
SITYG_RS10540 (SITYG_06180)	-	619617..620288 (-)	672	WP_231870256.1	hypothetical protein	-
SITYG_RS03215 (SITYG_06190)	comE/blpR	620290..621036 (-)	747	WP_041787711.1	response regulator transcription factor	Regulator
SITYG_RS03220 (SITYG_06200)	-	621205..621918 (-)	714	WP_096362646.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 80437.09 Da
• Isoelectric Point: 9.3439

>NTDB_id=67249 SITYG_RS03195 WP_096362643.1 615159..617309(+) (comA/nlmT) [Streptococcus intermedius strain TYG1620]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTVLGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKGKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKEIFATEWTGVAIFLAPEPSYKPHKDKKNGLISLIPLI
FKQKMLVTYIVLASLLVTLINIVGSYYLQGILDEYIPNQMRSTLGIVSIGLIITYILQQMMSFSRDYLLIVLSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLSILIIVGGVLLLQNTNLFFLTLLAIPIYTVI
IFAFIKPFEKMNHDVMQSNSMVNSAIIEDINGIETIKSLTSEEARYQKIDSEFVNYLDKSFTLSKYSIFQTTLKQGFQLI
LNVLILWLGAHLVISEKISIGQLITFTALLSYFTNSLESIINLQTKLQSAKVANKRLNEVYLVESEFKTKQTLIEKGFLA
GDITFHNVSYKYGFGRDTLSDINLTIKTGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFSGSILENLTLGTNQIFSQKEIIRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGSHAELMERQGFYHHLFNK

Nucleotide

• Length: 2151 bp

>NTDB_id=67249 SITYG_RS03195 WP_096362643.1 615159..617309(+) (comA/nlmT) [Streptococcus intermedius strain TYG1620]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTTGCGTCCATTGCAAAATA
TTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGTTCTTGGAATTG
TTCAAGCAGCGCAAGAAATAGGTTTTGAGACACGACCGATTCAAGGGGATATGTCTTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGGTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGACCCAAGTGTAAAAATAACCAAGATCTCAAAAGAAATATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAACCACATAAGGATAAGAAAAATGGTTTGATAAGCTTAATTCCTCTTATT
TTTAAACAGAAAATGCTGGTCACCTATATTGTTTTAGCTAGTCTGCTTGTGACACTCATCAATATTGTTGGATCTTACTA
CCTACAAGGAATTTTAGACGAATACATTCCAAATCAAATGAGATCAACTCTTGGAATAGTGTCTATTGGTCTGATTATTA
CTTATATTTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTGTACTTAGTCAGCGGCTGACCATCGATGTG
ATTTTATCATATATTCGACATATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTCTATTTTGATAA
TAGTAGGAGGGGTATTATTATTACAGAATACCAACCTTTTCTTCCTCACTCTGCTTGCTATTCCTATCTATACGGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATCATGACGTCATGCAAAGCAATTCTATGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACCATTAAATCTTTAACAAGCGAAGAAGCTCGTTACCAAAAGATAGACAGCGAATTTG
TAAATTATTTAGATAAATCTTTTACGCTTAGTAAATATTCTATTTTTCAAACAACTCTTAAACAAGGCTTTCAATTAATT
TTAAATGTGCTTATTTTATGGCTCGGTGCGCATTTAGTTATATCTGAGAAAATCTCAATTGGGCAGCTCATCACATTTAC
GGCTCTACTTTCTTATTTTACAAATTCTCTTGAAAGTATTATTAATCTGCAAACTAAGCTGCAATCGGCTAAGGTTGCTA
ACAAGCGGTTGAATGAAGTTTATTTAGTAGAGTCTGAATTTAAAACTAAGCAAACACTTATAGAGAAAGGTTTCTTGGCT
GGTGATATTACGTTCCATAATGTCTCCTATAAATACGGCTTCGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AACAGGAGATAAGGTGAGCTTAGTCGGCATCAGTGGTTCGGGAAAGACAACACTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTCAATGGAAATGACCTTAAAATGATTGATAAGAAGACGCTTCGTCAATATATCAAT
TATTTACCACAACAAGCCTATATTTTTAGTGGTTCCATCTTAGAAAATCTTACATTAGGGACGAATCAAATATTTTCTCA
AAAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATGCCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAACGAATTGCTCTAGCACGCGCCCTCTTAACAAAGTCACCAATT
CTTATTCTTGATGAAGCAACGAGCGGATTGGATGTTCTAACTGAGAAAAAGGTCATTGACAATCTGATGGGTTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGGACAAATCAGGTTATTGTTCTTGATAAAGGGCAGA
TTATTGAAACTGGATCCCACGCTGAATTGATGGAAAGACAAGGCTTTTATCATCATTTATTTAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (168-437)

• ABC transporter (ABC_tran) (499-648)

• Peptidase C39 family (Peptidase_C39) (6-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.932	99.022	0.712
comA	Streptococcus mitis NCTC 12261	66.62	99.581	0.663
comA	Streptococcus mitis SK321	66.48	99.581	0.662
comA	Streptococcus gordonii str. Challis substr. CH1	66.059	99.581	0.658
comA	Streptococcus pneumoniae D39	65.919	99.581	0.656
comA	Streptococcus pneumoniae R6	65.919	99.581	0.656
comA	Streptococcus pneumoniae Rx1	65.919	99.581	0.656
comA	Streptococcus pneumoniae TIGR4	65.498	99.581	0.652