Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   MUA18_RS02820 Genome accession   NZ_CP094780
Coordinates   587123..587692 (+) Length   189 a.a.
NCBI ID   WP_000872870.1    Uniprot ID   -
Organism   Staphylococcus aureus strain IVB6173     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 582123..592692
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA18_RS02795 (MUA18_02790) cysE 583336..583983 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  MUA18_RS02800 (MUA18_02795) cysS 583967..585367 (+) 1401 WP_262542183.1 cysteine--tRNA ligase -
  MUA18_RS02805 (MUA18_02800) - 585360..585764 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  MUA18_RS02810 (MUA18_02805) rlmB 585772..586518 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  MUA18_RS02815 (MUA18_02810) - 586518..587042 (+) 525 WP_000664738.1 NYN domain-containing protein -
  MUA18_RS02820 (MUA18_02815) sigH 587123..587692 (+) 570 WP_000872870.1 sigma-70 family RNA polymerase sigma factor Regulator
  MUA18_RS02825 (MUA18_02820) rpmG 587807..587950 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  MUA18_RS02830 (MUA18_02825) secE 588006..588188 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  MUA18_RS02835 (MUA18_02830) nusG 588201..588749 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  MUA18_RS02840 (MUA18_02835) rplK 588930..589352 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  MUA18_RS02845 (MUA18_02840) rplA 589560..590252 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  MUA18_RS02850 (MUA18_02845) rplJ 590524..591024 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  MUA18_RS02855 (MUA18_02850) rplL 591067..591435 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  MUA18_RS02860 (MUA18_02855) - 591610..592218 (+) 609 WP_000020308.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23083.93 Da        Isoelectric Point: 9.6015

>NTDB_id=672405 MUA18_RS02820 WP_000872870.1 587123..587692(+) (sigH) [Staphylococcus aureus strain IVB6173]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGDQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=672405 MUA18_RS02820 WP_000872870.1 587123..587692(+) (sigH) [Staphylococcus aureus strain IVB6173]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGACCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGCGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979