Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB49_RS35115 Genome accession   NZ_CP109178
Coordinates   7752808..7753458 (-) Length   216 a.a.
NCBI ID   WP_329164917.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01717     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7747808..7758458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB49_RS35095 (OHB49_35145) - 7748560..7749390 (-) 831 WP_329164912.1 alpha/beta fold hydrolase -
  OHB49_RS35100 (OHB49_35150) - 7749583..7750467 (+) 885 WP_329164914.1 RNA polymerase sigma-70 factor -
  OHB49_RS35105 (OHB49_35155) - 7750734..7751501 (+) 768 WP_030976374.1 GntR family transcriptional regulator -
  OHB49_RS35110 (OHB49_35160) - 7751551..7752708 (-) 1158 WP_329164916.1 ROK family protein -
  OHB49_RS35115 (OHB49_35165) vraR 7752808..7753458 (-) 651 WP_329164917.1 response regulator transcription factor Regulator
  OHB49_RS35120 (OHB49_35170) - 7753463..7754635 (-) 1173 WP_329164918.1 histidine kinase -
  OHB49_RS35125 (OHB49_35175) - 7754744..7755682 (+) 939 WP_329164919.1 ATP-binding cassette domain-containing protein -
  OHB49_RS35130 (OHB49_35180) - 7755679..7756422 (+) 744 WP_329166740.1 ABC transporter permease -
  OHB49_RS35135 (OHB49_35185) - 7756540..7756977 (+) 438 WP_329164921.1 hypothetical protein -
  OHB49_RS35140 (OHB49_35190) mug 7757053..7757610 (-) 558 WP_030976388.1 G/U mismatch-specific DNA glycosylase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23062.98 Da        Isoelectric Point: 7.3206

>NTDB_id=672167 OHB49_RS35115 WP_329164917.1 7752808..7753458(-) (vraR) [Streptomyces sp. NBC_01717]
MPVTVLLVDDEPLVRAGLRAVLEAQPDIKVVGEAADGAAVIPLVHRLRPDVVAMDVRMPLMDGIEATRVVLRTVPDPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPAAVRQLAAEYGTSKAKAVMKRASLTEREAAV
LRLMARGLSNAEIAAKLVVGVETVKSHVSAVLAKLGARDRTQAVIAAYESGFVAPS

Nucleotide


Download         Length: 651 bp        

>NTDB_id=672167 OHB49_RS35115 WP_329164917.1 7752808..7753458(-) (vraR) [Streptomyces sp. NBC_01717]
ATGCCGGTTACCGTTCTTCTGGTCGACGACGAACCTCTCGTACGCGCGGGGCTGCGCGCGGTCCTTGAGGCTCAGCCCGA
TATCAAGGTGGTGGGCGAGGCGGCCGACGGCGCGGCAGTGATCCCGCTGGTGCACAGGTTGCGCCCCGATGTGGTGGCGA
TGGATGTACGGATGCCCTTGATGGACGGCATCGAGGCGACCCGGGTGGTGCTGCGCACGGTGCCGGATCCGCCGAAGATC
CTGGTGGTGACGACATTCGAGAACGACGAGTACGTGTACGAGGCGCTGCGCGCCGGGGCGGACGGCTTCCTGCTCAAGCG
CGCCCGGCCCGCAGAGATCGTGCATGCGGTGCGCCTGGTCGCCGAGGGCGAGTCCCTGCTGTTCCCGGCCGCGGTCCGGC
AGCTCGCCGCCGAGTACGGGACGAGCAAGGCGAAGGCGGTCATGAAGCGGGCATCGCTCACCGAGCGCGAGGCTGCGGTG
CTCCGGTTGATGGCGCGGGGACTGTCGAATGCGGAGATCGCCGCCAAGCTCGTGGTCGGCGTCGAGACGGTGAAGAGTCA
TGTCAGCGCGGTGCTGGCCAAGTTGGGGGCCAGGGATCGGACCCAGGCGGTGATCGCCGCGTACGAGTCCGGGTTCGTTG
CTCCGAGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(152-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.475

100

0.417
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.375