Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   MUA94_RS06105 Genome accession   NZ_CP094768
Coordinates   1215617..1216591 (+) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain IVB6202     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1210617..1221591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA94_RS06070 (MUA94_06060) rpmG 1211077..1211226 (+) 150 WP_001265709.1 50S ribosomal protein L33 -
  MUA94_RS06075 (MUA94_06065) - 1211435..1211974 (+) 540 WP_262538808.1 5-formyltetrahydrofolate cyclo-ligase -
  MUA94_RS06080 (MUA94_06070) - 1211986..1213449 (+) 1464 WP_250743365.1 rhomboid family intramembrane serine protease -
  MUA94_RS06085 (MUA94_06075) - 1213430..1213633 (+) 204 WP_000087561.1 YqgQ family protein -
  MUA94_RS06090 (MUA94_06080) - 1213630..1214616 (+) 987 WP_000161315.1 ROK family glucokinase -
  MUA94_RS06095 (MUA94_06085) - 1214616..1214945 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  MUA94_RS06100 (MUA94_06090) - 1214942..1215565 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  MUA94_RS06105 (MUA94_06095) comGA 1215617..1216591 (+) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  MUA94_RS06110 (MUA94_06100) comGB 1216563..1217633 (+) 1071 WP_262538679.1 competence type IV pilus assembly protein ComGB Machinery gene
  MUA94_RS06115 (MUA94_06105) comGC 1217647..1217958 (+) 312 WP_262538680.1 competence type IV pilus major pilin ComGC Machinery gene
  MUA94_RS06120 (MUA94_06110) comGD 1217936..1218382 (+) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  MUA94_RS06125 (MUA94_06115) comGE 1218369..1218668 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  MUA94_RS06130 (MUA94_06120) comGF 1218586..1219083 (+) 498 WP_258411170.1 competence type IV pilus minor pilin ComGF Machinery gene
  MUA94_RS06135 (MUA94_06125) - 1219180..1219326 (+) 147 WP_001789879.1 hypothetical protein -
  MUA94_RS06140 (MUA94_06130) - 1219316..1219840 (+) 525 WP_001015120.1 shikimate kinase -
  MUA94_RS06145 (MUA94_06135) gcvT 1219999..1221090 (+) 1092 WP_262538681.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=672167 MUA94_RS06105 WP_000697220.1 1215617..1216591(+) (comGA) [Staphylococcus aureus strain IVB6202]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=672167 MUA94_RS06105 WP_000697220.1 1215617..1216591(+) (comGA) [Staphylococcus aureus strain IVB6202]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTACCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1