Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   MUA45_RS08925 Genome accession   NZ_CP094765
Coordinates   1784264..1784950 (-) Length   228 a.a.
NCBI ID   WP_001794049.1    Uniprot ID   A0A0E1X4U4
Organism   Staphylococcus aureus strain IVB6215     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1779264..1789950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA45_RS08905 (MUA45_08900) - 1779582..1781450 (-) 1869 Protein_1754 DNA internalization-related competence protein ComEC/Rec2 -
  MUA45_RS08910 (MUA45_08905) - 1781469..1783115 (-) 1647 WP_020967614.1 IS1182-like element ISSau3 family transposase -
  MUA45_RS08915 (MUA45_08910) - 1783395..1783706 (-) 312 Protein_1756 DNA internalization-related competence protein ComEC/Rec2 -
  MUA45_RS08920 (MUA45_08915) - 1783711..1784172 (-) 462 WP_000439692.1 ComE operon protein 2 -
  MUA45_RS08925 (MUA45_08920) comEA 1784264..1784950 (-) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  MUA45_RS08930 (MUA45_08925) - 1784990..1785706 (-) 717 WP_000084835.1 class I SAM-dependent DNA methyltransferase -
  MUA45_RS08935 (MUA45_08930) rsfS 1785709..1786062 (-) 354 WP_001088020.1 ribosome silencing factor -
  MUA45_RS08940 (MUA45_08935) yqeK 1786063..1786647 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  MUA45_RS08945 (MUA45_08940) nadD 1786637..1787206 (-) 570 WP_000822938.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  MUA45_RS08950 (MUA45_08945) yhbY 1787209..1787499 (-) 291 WP_000955232.1 ribosome assembly RNA-binding protein YhbY -
  MUA45_RS08955 (MUA45_08950) aroE 1787503..1788309 (-) 807 WP_000666750.1 shikimate dehydrogenase -
  MUA45_RS08960 (MUA45_08955) yqeH 1788323..1789423 (-) 1101 WP_001280133.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25766.38 Da        Isoelectric Point: 9.3383

>NTDB_id=672130 MUA45_RS08925 WP_001794049.1 1784264..1784950(-) (comEA) [Staphylococcus aureus strain IVB6215]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=672130 MUA45_RS08925 WP_001794049.1 1784264..1784950(-) (comEA) [Staphylococcus aureus strain IVB6215]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X4U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

95.595

99.561

0.952
  comEA Staphylococcus aureus N315

95.595

99.561

0.952