Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OIE75_RS05590 Genome accession   NZ_CP109171
Coordinates   1175604..1176269 (+) Length   221 a.a.
NCBI ID   WP_307010163.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01723     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1170604..1181269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OIE75_RS05565 (OIE75_05580) mug 1171647..1172198 (+) 552 WP_185832201.1 G/U mismatch-specific DNA glycosylase -
  OIE75_RS05570 (OIE75_05585) - 1172176..1172619 (-) 444 WP_307010158.1 hypothetical protein -
  OIE75_RS05575 (OIE75_05590) - 1172678..1173403 (-) 726 WP_329469773.1 ABC transporter permease -
  OIE75_RS05580 (OIE75_05595) - 1173406..1174326 (-) 921 WP_329469774.1 ATP-binding cassette domain-containing protein -
  OIE75_RS05585 (OIE75_05600) - 1174435..1175589 (+) 1155 WP_329469775.1 histidine kinase -
  OIE75_RS05590 (OIE75_05605) vraR 1175604..1176269 (+) 666 WP_307010163.1 response regulator transcription factor Regulator
  OIE75_RS05595 (OIE75_05610) - 1176370..1177524 (+) 1155 WP_161328024.1 ROK family transcriptional regulator -
  OIE75_RS05600 (OIE75_05615) - 1177556..1178317 (-) 762 WP_307010166.1 GntR family transcriptional regulator -
  OIE75_RS05605 (OIE75_05620) - 1178434..1179321 (-) 888 WP_329469777.1 RNA polymerase sigma-70 factor -
  OIE75_RS05610 (OIE75_05625) - 1179449..1180327 (+) 879 WP_329469778.1 alpha/beta fold hydrolase -
  OIE75_RS05615 (OIE75_05630) - 1180279..1181148 (-) 870 WP_329469779.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23682.24 Da        Isoelectric Point: 5.0083

>NTDB_id=671939 OIE75_RS05590 WP_307010163.1 1175604..1176269(+) (vraR) [Streptomyces sp. NBC_01723]
MPVRVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVVPLVRQLRPDVVAMDVRMPLLDGIEATRALLRTVADPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLIAEGESLLFPASVRQLATEYGDDGGGNRAARATVERARLTE
REGEVLRLMSRGLSNAEIAARLVVGTETVKSHVSAVLAKLGARDRTQAVITAYESGFVAPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=671939 OIE75_RS05590 WP_307010163.1 1175604..1176269(+) (vraR) [Streptomyces sp. NBC_01723]
ATGCCGGTCAGAGTGCTCCTCGTCGACGACGAACCCCTCGTACGCGCGGGTCTGCGGGCCGTGCTGGAGGCGCAGCCGGA
CATCGAGGTCGTCGGCGAGGCGGCGGACGGGGCGGCGGTCGTCCCGCTGGTGCGTCAGCTGCGGCCGGACGTGGTCGCCA
TGGACGTCCGGATGCCGCTGCTCGACGGCATCGAGGCGACGCGCGCGCTGCTGCGGACGGTGGCCGACCCGCCGAAGATC
CTCGTGGTGACGACCTTCGAGAACGACGAGTACGTGTACGAGGCGCTGCGCGCGGGTGCGGACGGGTTTCTGCTCAAGCG
CGCCCGGCCGGCCGAGATCGTGCACGCGGTCCGGCTGATCGCCGAGGGCGAGTCGCTGCTGTTCCCCGCCTCGGTGCGGC
AACTGGCCACCGAGTACGGCGACGACGGCGGCGGGAACCGGGCGGCCCGTGCCACGGTGGAGCGGGCGCGGCTGACCGAA
CGGGAGGGCGAGGTGCTGCGGCTGATGTCGCGCGGGCTGTCGAACGCGGAGATCGCCGCCCGGCTGGTCGTCGGCACGGA
GACGGTGAAGTCGCATGTGAGCGCGGTACTGGCGAAGCTGGGGGCACGGGACCGCACGCAGGCGGTGATCACGGCGTACG
AGTCGGGATTCGTGGCGCCGGGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-212)

Response regulator receiver domain (Response_reg)

(5-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40

99.548

0.398
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.362