Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   MUA08_RS08590 Genome accession   NZ_CP094747
Coordinates   1731909..1732595 (-) Length   228 a.a.
NCBI ID   WP_001794049.1    Uniprot ID   A0A0E1X4U4
Organism   Staphylococcus aureus strain IVB6249     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1726909..1737595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA08_RS08570 (MUA08_08570) - 1727227..1729095 (-) 1869 Protein_1686 DNA internalization-related competence protein ComEC/Rec2 -
  MUA08_RS08575 (MUA08_08575) - 1729114..1730760 (-) 1647 WP_020967614.1 IS1182-like element ISSau3 family transposase -
  MUA08_RS08580 (MUA08_08580) - 1731040..1731351 (-) 312 Protein_1688 DNA internalization-related competence protein ComEC/Rec2 -
  MUA08_RS08585 (MUA08_08585) - 1731356..1731817 (-) 462 WP_000439692.1 ComE operon protein 2 -
  MUA08_RS08590 (MUA08_08590) comEA 1731909..1732595 (-) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  MUA08_RS08595 (MUA08_08595) - 1732635..1733351 (-) 717 WP_000084835.1 class I SAM-dependent methyltransferase -
  MUA08_RS08600 (MUA08_08600) rsfS 1733354..1733707 (-) 354 WP_001088020.1 ribosome silencing factor -
  MUA08_RS08605 (MUA08_08605) yqeK 1733708..1734292 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  MUA08_RS08610 (MUA08_08610) nadD 1734282..1734851 (-) 570 WP_000822938.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  MUA08_RS08615 (MUA08_08615) yhbY 1734854..1735144 (-) 291 WP_000955232.1 ribosome assembly RNA-binding protein YhbY -
  MUA08_RS08620 (MUA08_08620) aroE 1735148..1735954 (-) 807 WP_000666750.1 shikimate dehydrogenase -
  MUA08_RS08625 (MUA08_08625) yqeH 1735968..1737068 (-) 1101 WP_001280133.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25766.38 Da        Isoelectric Point: 9.3383

>NTDB_id=671882 MUA08_RS08590 WP_001794049.1 1731909..1732595(-) (comEA) [Staphylococcus aureus strain IVB6249]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=671882 MUA08_RS08590 WP_001794049.1 1731909..1732595(-) (comEA) [Staphylococcus aureus strain IVB6249]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X4U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

95.595

99.561

0.952
  comEA Staphylococcus aureus N315

95.595

99.561

0.952