Detailed information NTG0671687

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA44_RS04490
• Genome accession: NZ_CP094740
• Coordinates: 996500..997543 (+)
• Length: 347 a.a.
• NCBI ID: WP_019166463.1
• Uniprot ID: A0A2A4GVQ0
• Organism: Staphylococcus delphini strain IVB6190
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 991500..1002543

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA44_RS04465 (MUA44_04460)	-	992565..993290 (+)	726	WP_019166458.1	type 1 glutamine amidotransferase	-
MUA44_RS04470 (MUA44_04465)	-	993446..994444 (-)	999	WP_019166459.1	aromatic acid exporter family protein	-
MUA44_RS04475 (MUA44_04470)	map	994541..995302 (+)	762	WP_262613444.1	type I methionyl aminopeptidase	-
MUA44_RS04480 (MUA44_04475)	-	995400..995789 (+)	390	WP_262613446.1	hypothetical protein	-
MUA44_RS04485 (MUA44_04480)	liaF	995802..996503 (+)	702	WP_096557032.1	cell wall-active antibiotics response protein LiaF	-
MUA44_RS04490 (MUA44_04485)	vraS	996500..997543 (+)	1044	WP_019166463.1	sensor histidine kinase	Regulator
MUA44_RS04495 (MUA44_04490)	vraR	997533..998162 (+)	630	WP_014613482.1	response regulator transcription factor	Regulator
MUA44_RS04500 (MUA44_04495)	-	998316..998897 (-)	582	WP_019166464.1	carbonic anhydrase	-
MUA44_RS04505 (MUA44_04500)	-	998930..1000276 (-)	1347	WP_262613447.1	YihY/virulence factor BrkB family protein	-
MUA44_RS04510 (MUA44_04505)	-	1000492..1000779 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
MUA44_RS04515 (MUA44_04510)	-	1000787..1001245 (-)	459	WP_262613448.1	low molecular weight protein-tyrosine-phosphatase	-
MUA44_RS04520 (MUA44_04515)	-	1001379..1001582 (+)	204	WP_019166467.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39911.18 Da
• Isoelectric Point: 5.0397

>NTDB_id=671687 MUA44_RS04490 WP_019166463.1 996500..997543(+) (vraS) [Staphylococcus delphini strain IVB6190]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWVKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDDKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=671687 MUA44_RS04490 WP_019166463.1 996500..997543(+) (vraS) [Staphylococcus delphini strain IVB6190]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATCGATAA
AGTGTTTACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGGATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATCGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGGTGAAGCAA
CAAATTGTTCGTGCTTTCGAAGGCGAAACAGTGGGAATCAATGATCAACAACTTGAGCTGTATAATGAAACGATTGAATT
GTATCAAGCGCTTGTCCCATTGAATCAAGAACTGCATAAAATGCGGATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGGCAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAGGAAACAGATTTAGCTCCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGTGCACTGTTACTTCATTTGAGACCTATAGGATTGAAGG
ACAAATCGTTAGGTGAGGGGATAAAATCGCTTGTGACGGATCTACAGCGCAAAGTGCCTATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTCCCTAAAGGTATTGAGGATCACCTCTTTAGGATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGAACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGATAAATTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACG
TTTCATATCGTCTCATTACCTGATGCAGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A2A4GVQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.573	100	0.836