Detailed information NTG0671590

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA33_RS04590
• Genome accession: NZ_CP094736
• Coordinates: 965694..966737 (+)
• Length: 347 a.a.
• NCBI ID: WP_019166463.1
• Uniprot ID: A0A2A4GVQ0
• Organism: Staphylococcus delphini strain IVB6222
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 960694..971737

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA33_RS04565 (MUA33_04555)	-	960907..961629 (+)	723	WP_096597671.1	type 1 glutamine amidotransferase	-
MUA33_RS04570 (MUA33_04560)	-	962640..963638 (-)	999	WP_262611975.1	aromatic acid exporter family protein	-
MUA33_RS04575 (MUA33_04565)	map	963735..964496 (+)	762	WP_019166460.1	type I methionyl aminopeptidase	-
MUA33_RS04580 (MUA33_04570)	-	964594..964983 (+)	390	WP_262631190.1	hypothetical protein	-
MUA33_RS04585 (MUA33_04575)	liaF	964996..965697 (+)	702	WP_096597675.1	cell wall-active antibiotics response protein LiaF	-
MUA33_RS04590 (MUA33_04580)	vraS	965694..966737 (+)	1044	WP_019166463.1	sensor histidine kinase	Regulator
MUA33_RS04595 (MUA33_04585)	vraR	966727..967356 (+)	630	WP_262631191.1	response regulator transcription factor	Regulator
MUA33_RS04600 (MUA33_04590)	-	967990..968571 (-)	582	WP_096597677.1	carbonic anhydrase	-
MUA33_RS04605 (MUA33_04595)	-	968604..969950 (-)	1347	WP_262631193.1	YihY/virulence factor BrkB family protein	-
MUA33_RS04610 (MUA33_04600)	-	970166..970453 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
MUA33_RS04615 (MUA33_04605)	-	970461..970919 (-)	459	WP_262611980.1	low molecular weight protein-tyrosine-phosphatase	-
MUA33_RS04620 (MUA33_04610)	-	971053..971256 (+)	204	WP_019169369.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39911.18 Da
• Isoelectric Point: 5.0397

>NTDB_id=671590 MUA33_RS04590 WP_019166463.1 965694..966737(+) (vraS) [Staphylococcus delphini strain IVB6222]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWVKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDDKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=671590 MUA33_RS04590 WP_019166463.1 965694..966737(+) (vraS) [Staphylococcus delphini strain IVB6222]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATCGATAA
AGTGTTTACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGGATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATCGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGGTGAAGCAA
CAAATCGTTCGTGCTTTCGAAGGCGAAACAGTGGGAATCAATGATCAACAACTTGAGCTGTATAATGAAACGATTGAATT
GTACCAAGCGCTCGTCCCATTGAATCAAGAACTGCATAAAATGCGGATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGGCAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAGGAAACAGATTTAGCTCCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGTGCACTGTTACTTCATTTAAGACCTATAGGATTGAAGG
ATAAATCGTTAGGTGAGGGGATAAAATCGCTCGTGACGGATTTACAACGCAAAGTGCCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTCCCTAAAGGTATTGAGGATCACCTTTTTAGGATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGAACGCAAGTAACAGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGATAAATTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACG
TTTCATATCGTCTCATTACCTGATGCAGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A2A4GVQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.573	100	0.836