Detailed information NTG0671186

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: MUA74_RS00560
• Genome accession: NZ_CP094720
• Coordinates: 131960..133591 (-)
• Length: 543 a.a.
• NCBI ID: WP_262609300.1
• Uniprot ID: A0A9Q9K4U7
• Organism: Staphylococcus sp. IVB6233
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	112918..131494	131960..133591	flank	466

Gene organization within MGE regions

Location: 112918..133591

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA74_RS00450 (MUA74_00450)	-	112918..113229 (+)	312	WP_105966009.1	DUF960 family protein	-
MUA74_RS00455 (MUA74_00455)	-	113242..113751 (+)	510	WP_037576892.1	DUF1643 domain-containing protein	-
MUA74_RS00460 (MUA74_00460)	-	113770..113985 (+)	216	WP_031886433.1	hypothetical protein	-
MUA74_RS00465 (MUA74_00465)	-	114193..115071 (+)	879	WP_262605603.1	HTH domain-containing protein	-
MUA74_RS00470 (MUA74_00470)	-	115572..115874 (+)	303	WP_262605604.1	hypothetical protein	-
MUA74_RS00475 (MUA74_00475)	-	115881..116060 (+)	180	WP_037576880.1	hypothetical protein	-
MUA74_RS00480 (MUA74_00480)	-	116092..116868 (+)	777	WP_051605018.1	EcsC family protein	-
MUA74_RS00485 (MUA74_00485)	-	116999..120121 (-)	3123	WP_262605605.1	type I restriction endonuclease subunit R	-
MUA74_RS00490 (MUA74_00490)	-	120105..121376 (-)	1272	WP_262605606.1	restriction endonuclease subunit S	-
MUA74_RS00495 (MUA74_00495)	-	121366..122880 (-)	1515	WP_262605607.1	class I SAM-dependent DNA methyltransferase	-
MUA74_RS00500 (MUA74_00500)	-	123305..123565 (+)	261	WP_262605608.1	hypothetical protein	-
MUA74_RS00505 (MUA74_00505)	-	123562..123943 (+)	382	Protein_98	FAD-dependent oxidoreductase	-
MUA74_RS00510 (MUA74_00510)	-	124122..124547 (-)	426	WP_262605609.1	pyridoxamine 5'-phosphate oxidase family protein	-
MUA74_RS00515 (MUA74_00515)	-	124731..126104 (+)	1374	WP_262605610.1	deoxyribodipyrimidine photo-lyase	-
MUA74_RS00520 (MUA74_00520)	-	126135..126557 (+)	423	WP_262605611.1	antibiotic biosynthesis monooxygenase	-
MUA74_RS00525 (MUA74_00525)	-	127136..128230 (-)	1095	WP_262609294.1	IS30 family transposase	-
MUA74_RS00530 (MUA74_00530)	-	128285..128719 (-)	435	WP_262609295.1	hypothetical protein	-
MUA74_RS00535 (MUA74_00535)	-	128970..129308 (-)	339	WP_262609296.1	hypothetical protein	-
MUA74_RS00540 (MUA74_00540)	-	129298..129789 (-)	492	WP_262609297.1	hypothetical protein	-
MUA74_RS00545 (MUA74_00545)	-	130228..130731 (-)	504	WP_262609298.1	DUF1643 domain-containing protein	-
MUA74_RS00550 (MUA74_00550)	-	130746..131057 (-)	312	WP_031912426.1	DUF960 family protein	-
MUA74_RS00555 (MUA74_00555)	-	131153..131491 (-)	339	WP_262609299.1	SAUGI family uracil-DNA glycosylase inhibitor	-
MUA74_RS00560 (MUA74_00560)	ccrB	131960..133591 (-)	1632	WP_262609300.1	recombinase family protein	Machinery gene

Sequence

Protein

• Length: 543 a.a.
• Molecular weight: 62374.23 Da
• Isoelectric Point: 9.6343

>NTDB_id=671186 MUA74_RS00560 WP_262609300.1 131960..133591(-) (ccrB) [Staphylococcus sp. IVB6233]
MEKLKQKRVGIYVRVSTEMQSSEGYSITGQINQIEEYCQFNNFKVVDVYADRGISGKSMNRPALQRMLQDAKNGHIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVSTSSGKLMLQVLASFAEFERNNIVDNIFTGQTIRAKEGYYQGN
IPYAYDKVPDSKHELMINQHEANVVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSISAVTYILSNPFYVGKIQFAK
YKDWNDKRRKGLNDKPVIAEGKHTPIISQTLWDKVQARKKQVSEKPQVHGKGTNLLTGLISCERCGAAYAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVIKQVVERVNQEHQIDTSALNHDIAYKQQQYD
EVQIKLDNLIKTLEDNPDLTSVLKNTIHQYEKQLNDITNQINQLKQQQSAPKTIYDANEIATILRHIFKNIETMDKAQLK
ALYLTVIDHIDIRKDEHHKKQFYVTLKLNHEIIKQLFHNTPLDEVQLSTSSLLLSQTLYLPIS

Nucleotide

• Length: 1632 bp

>NTDB_id=671186 MUA74_RS00560 WP_262609300.1 131960..133591(-) (ccrB) [Staphylococcus sp. IVB6233]
ATGGAAAAACTTAAACAAAAGCGTGTGGGAATTTATGTACGCGTATCGACTGAGATGCAGAGCTCAGAAGGCTACTCGAT
AACAGGCCAGATCAATCAGATTGAAGAATACTGTCAATTTAATAACTTCAAAGTGGTAGATGTATACGCAGATCGTGGTA
TTTCCGGAAAATCTATGAACCGCCCTGCACTACAACGTATGTTACAAGACGCTAAAAATGGTCATATCGATTGTGTTATG
GTCTACAAAACAAATCGATTAGCACGTAATACATCTGACCTACTCAAAATCGTTGAAGATTTGCATAAACAAAATGTCGA
ATTTTTCAGTCTGTCTGAACGTATGGAAGTTAGCACGAGTAGTGGTAAGCTCATGCTCCAGGTGCTTGCGAGCTTCGCAG
AATTTGAACGCAATAATATTGTAGACAATATATTTACGGGCCAGACAATTAGAGCGAAAGAAGGGTATTATCAGGGTAAT
ATTCCCTATGCGTATGATAAAGTACCTGACAGTAAACACGAACTTATGATTAATCAACATGAAGCCAATGTTGTAAAGTA
TATCTTCGAATCATATGCCAAAGGGCATGGCTATCGTAAAATTGCCAATGCGCTCAACCATAAAGGTTATGTCACAAAGA
AAGGGAATCCATTTAGTATTTCAGCTGTTACTTATATTCTCTCTAATCCCTTCTATGTCGGTAAAATACAATTCGCGAAA
TACAAAGATTGGAATGATAAACGACGTAAAGGGTTAAATGATAAACCCGTAATTGCCGAAGGCAAACACACCCCTATTAT
TAGCCAAACATTATGGGATAAAGTACAAGCACGTAAAAAACAAGTAAGTGAAAAACCACAAGTACATGGTAAAGGAACCA
ACCTTTTGACTGGATTAATTTCGTGTGAAAGATGTGGAGCGGCATACGCAGCATCGAATACAACGAATACACTTAAAGAT
GGTACTAAAAAACGCATTCGCTACTATTCATGTAGTAACTTTCGTAATAAAGGGTCAAAAGTATGTTCTGCGAATAGTGT
CAGAGCCGATGTAATTGAAAAATATGTTATGGATCAAATACTCGAAATCGTTAAAAGTGACAAAGTTATCAAACAAGTCG
TTGAGCGTGTCAATCAAGAACATCAAATTGATACGTCTGCACTCAATCATGATATCGCATATAAGCAACAACAATATGAT
GAGGTCCAAATCAAATTAGATAACTTGATCAAAACACTTGAAGATAATCCAGACTTAACATCTGTGCTTAAAAATACGAT
TCATCAGTATGAAAAACAACTCAATGACATCACAAATCAAATCAATCAACTTAAGCAACAACAAAGTGCTCCCAAAACAA
TATATGACGCTAATGAGATTGCGACTATATTACGTCATATATTCAAAAATATCGAAACCATGGATAAAGCACAACTCAAA
GCACTATACCTTACGGTCATAGACCACATTGATATTCGTAAAGACGAACATCATAAAAAACAGTTCTACGTCACATTAAA
ACTCAATCATGAAATCATTAAACAACTCTTCCATAATACCCCTCTCGACGAAGTGCAACTCAGCACTTCGTCTTTATTAT
TATCTCAAACACTCTATTTGCCTATCTCATAA

Domains

Predicted by InterproScan.

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (295-360)

• Resolvase, N terminal domain (Resolvase) (11-155)

• Recombinase (Recombinase) (180-280)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	81.365	99.816	0.812