Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUA48_RS07750 Genome accession   NZ_CP094719
Coordinates   1555744..1556373 (-) Length   209 a.a.
NCBI ID   WP_262603540.1    Uniprot ID   -
Organism   Staphylococcus sp. IVB6238     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1550744..1561373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA48_RS07720 (MUA48_07690) - 1550897..1552135 (-) 1239 WP_262603535.1 aminopeptidase -
  MUA48_RS07725 (MUA48_07695) - 1552150..1552356 (-) 207 WP_262605142.1 DUF1128 domain-containing protein -
  MUA48_RS07730 (MUA48_07700) - 1552589..1553050 (+) 462 WP_262603536.1 low molecular weight protein-tyrosine-phosphatase -
  MUA48_RS07735 (MUA48_07705) - 1553050..1553340 (+) 291 WP_262603537.1 YtxH domain-containing protein -
  MUA48_RS07740 (MUA48_07710) - 1553522..1554820 (+) 1299 WP_262603538.1 YihY/virulence factor BrkB family protein -
  MUA48_RS07745 (MUA48_07715) - 1555115..1555693 (+) 579 WP_262603539.1 carbonic anhydrase -
  MUA48_RS07750 (MUA48_07720) vraR 1555744..1556373 (-) 630 WP_262603540.1 response regulator transcription factor Regulator
  MUA48_RS07755 (MUA48_07725) vraS 1556363..1557406 (-) 1044 WP_262603541.1 sensor histidine kinase Regulator
  MUA48_RS07760 (MUA48_07730) liaF 1557403..1558107 (-) 705 WP_262603542.1 cell wall-active antibiotics response protein LiaF -
  MUA48_RS07765 (MUA48_07735) - 1558120..1558509 (-) 390 WP_262603543.1 hypothetical protein -
  MUA48_RS07770 (MUA48_07740) map 1558608..1559369 (-) 762 WP_262603544.1 type I methionyl aminopeptidase -
  MUA48_RS07775 (MUA48_07745) - 1559464..1560462 (+) 999 WP_262603545.1 aromatic acid exporter family protein -
  MUA48_RS07780 (MUA48_07750) - 1560532..1561257 (-) 726 WP_262603546.1 glutamine amidotransferase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23334.93 Da        Isoelectric Point: 4.8810

>NTDB_id=671175 MUA48_RS07750 WP_262603540.1 1555744..1556373(-) (vraR) [Staphylococcus sp. IVB6238]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGGSGREAIEKAHELKPDVILMDLVMTDMDGVEATAQIKKDLPAIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSASDIASAIRKTSQGESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=671175 MUA48_RS07750 WP_262603540.1 1555744..1556373(-) (vraR) [Staphylococcus sp. IVB6238]
ATGACGATTAAAGTTTTGTTTGTAGATGATCATGAAATGGTTCGTATTGGTATTTCTAGTTATTTATCGACTCAGCCAGA
CATTGAAGTGGTCGGTGAGGGCGGTTCAGGTAGAGAAGCCATTGAAAAAGCACATGAATTAAAGCCTGATGTTATCTTGA
TGGACCTTGTGATGACAGATATGGATGGTGTGGAAGCGACAGCACAAATAAAAAAAGACCTACCAGCAATTAAAGTCGTA
ATGTTAACGAGCTACATAGAGGATAAAGAAGTCTATCGTGCCTTAGATGCGGGTGTGGATAGTTATATTCTTAAAACGAC
AAGTGCGAGTGATATTGCGTCTGCGATACGTAAGACAAGCCAAGGAGAGTCAGTATTTGAAGCGGAAGTCTTGGTTAAAA
TGCGTAACCGTATGAAGCAGCGTGCAGAATTATATGAGATGTTAACAGAAAGAGAGATGGAGATTCTTTTACTGATTGCA
AAAGGATACTCCAATCAAGAAATTGCGAGTGCCTCACATATTACGATTAAAACCGTTAAAACTCATGTGAGTAATATTTT
AAGTAAGTTGGAAGTACAAGACCGTACACAAGCGGTCATTTATGCTTTCCAACATGGTTTGATTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.909

100

0.909
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383