Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUA73_RS05240 Genome accession   NZ_CP094696
Coordinates   1135747..1136376 (+) Length   209 a.a.
NCBI ID   WP_002481662.1    Uniprot ID   -
Organism   Staphylococcus simulans strain IVB6251     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1130747..1141376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA73_RS05215 (MUA73_05215) - 1131519..1132505 (-) 987 WP_002481667.1 aromatic acid exporter family protein -
  MUA73_RS05220 (MUA73_05220) map 1132725..1133489 (+) 765 WP_002481666.1 type I methionyl aminopeptidase -
  MUA73_RS05225 (MUA73_05225) - 1133605..1134000 (+) 396 WP_262557920.1 hypothetical protein -
  MUA73_RS05230 (MUA73_05230) liaF 1134016..1134717 (+) 702 WP_002481664.1 cell wall-active antibiotics response protein LiaF -
  MUA73_RS05235 (MUA73_05235) vraS 1134714..1135757 (+) 1044 WP_002481663.1 sensor histidine kinase Regulator
  MUA73_RS05240 (MUA73_05240) vraR 1135747..1136376 (+) 630 WP_002481662.1 response regulator transcription factor Regulator
  MUA73_RS05245 (MUA73_05245) - 1136447..1137025 (-) 579 WP_002481661.1 carbonic anhydrase -
  MUA73_RS05250 (MUA73_05250) - 1137234..1138310 (-) 1077 WP_262557921.1 YihY/virulence factor BrkB family protein -
  MUA73_RS05255 (MUA73_05255) - 1138441..1138731 (-) 291 WP_002481659.1 hypothetical protein -
  MUA73_RS05260 (MUA73_05260) - 1138739..1139203 (-) 465 WP_023015860.1 low molecular weight protein-tyrosine-phosphatase -
  MUA73_RS05265 (MUA73_05265) - 1139427..1139633 (+) 207 WP_002481657.1 DUF1128 family protein -
  MUA73_RS05270 (MUA73_05270) - 1139670..1140908 (+) 1239 WP_070626228.1 aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23719.32 Da        Isoelectric Point: 4.6245

>NTDB_id=670690 MUA73_RS05240 WP_002481662.1 1135747..1136376(+) (vraR) [Staphylococcus simulans strain IVB6251]
MAIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGKSGKEAIEKAHELQPDLILMDLLMEDMDGVEATMQIKKDLPQIKVL
MLTSYIEDNEVYRALDAGVDSYILKTTSASDIAEAIRKTYRNEAVFEAEVLVKMRNRMNQRAELYELLTDREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHDLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=670690 MUA73_RS05240 WP_002481662.1 1135747..1136376(+) (vraR) [Staphylococcus simulans strain IVB6251]
ATGGCGATTAAAGTATTATTTGTCGATGACCACGAAATGGTTCGTATCGGAATCTCAAGTTATTTATCTACACAACCTGA
TATCGAAGTCGTCGGGGAAGGCAAATCAGGTAAAGAAGCAATTGAAAAAGCTCATGAATTGCAGCCTGATTTAATTTTGA
TGGATTTGTTGATGGAAGACATGGATGGCGTAGAAGCTACAATGCAGATTAAAAAAGATTTACCTCAGATTAAAGTATTG
ATGCTGACAAGTTATATTGAGGATAATGAAGTGTATCGTGCTTTAGACGCTGGGGTAGACAGTTATATTCTAAAAACGAC
GAGCGCAAGTGATATCGCAGAAGCGATTCGTAAAACATATCGTAACGAAGCGGTGTTTGAAGCGGAAGTACTTGTTAAAA
TGCGTAATCGCATGAATCAACGTGCTGAATTATATGAATTATTAACAGATAGAGAAATGGAAATTTTATTGTTAATCGCA
AAAGGTTATTCTAACCAAGAAATTGCCAGTGCGTCACATATTACGATTAAAACAGTTAAAACACATGTGAGTAATATATT
AAGCAAGCTAGAAGTTCAAGACAGAACACAAGCTGTTATTTACGCATTCCAACACGATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.431

100

0.904
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368