Detailed information NTG0670689

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA73_RS05235
• Genome accession: NZ_CP094696
• Coordinates: 1134714..1135757 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain IVB6251
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1129714..1140757

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA73_RS05210 (MUA73_05210)	-	1130717..1131436 (+)	720	WP_002481668.1	type 1 glutamine amidotransferase	-
MUA73_RS05215 (MUA73_05215)	-	1131519..1132505 (-)	987	WP_002481667.1	aromatic acid exporter family protein	-
MUA73_RS05220 (MUA73_05220)	map	1132725..1133489 (+)	765	WP_002481666.1	type I methionyl aminopeptidase	-
MUA73_RS05225 (MUA73_05225)	-	1133605..1134000 (+)	396	WP_262557920.1	hypothetical protein	-
MUA73_RS05230 (MUA73_05230)	liaF	1134016..1134717 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
MUA73_RS05235 (MUA73_05235)	vraS	1134714..1135757 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
MUA73_RS05240 (MUA73_05240)	vraR	1135747..1136376 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
MUA73_RS05245 (MUA73_05245)	-	1136447..1137025 (-)	579	WP_002481661.1	carbonic anhydrase	-
MUA73_RS05250 (MUA73_05250)	-	1137234..1138310 (-)	1077	WP_262557921.1	YihY/virulence factor BrkB family protein	-
MUA73_RS05255 (MUA73_05255)	-	1138441..1138731 (-)	291	WP_002481659.1	hypothetical protein	-
MUA73_RS05260 (MUA73_05260)	-	1138739..1139203 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
MUA73_RS05265 (MUA73_05265)	-	1139427..1139633 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=670689 MUA73_RS05235 WP_002481663.1 1134714..1135757(+) (vraS) [Staphylococcus simulans strain IVB6251]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=670689 MUA73_RS05235 WP_002481663.1 1134714..1135757(+) (vraS) [Staphylococcus simulans strain IVB6251]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATATTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTATACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAATTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGGGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCACTTGATCAGCAAATTCC
GACATTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATAACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTATTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862