Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG788_RS12285 Genome accession   NZ_CP109040
Coordinates   2788110..2788751 (-) Length   213 a.a.
NCBI ID   WP_266757150.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00647     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2783110..2793751
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG788_RS12255 (OG788_12285) - 2783537..2784496 (-) 960 WP_328668065.1 SPFH domain-containing protein -
  OG788_RS12260 (OG788_12290) - 2784627..2785061 (-) 435 WP_351556244.1 NfeD family protein -
  OG788_RS12265 (OG788_12295) - 2785159..2785950 (-) 792 WP_266757144.1 ABC transporter ATP-binding protein -
  OG788_RS12270 (OG788_12300) - 2786072..2786860 (+) 789 WP_406370682.1 hypothetical protein -
  OG788_RS12275 (OG788_12305) - 2787184..2787423 (-) 240 WP_351556237.1 chaplin -
  OG788_RS12280 (OG788_12310) - 2787622..2787867 (-) 246 WP_351556234.1 chaplin -
  OG788_RS12285 (OG788_12315) vraR 2788110..2788751 (-) 642 WP_266757150.1 response regulator transcription factor Regulator
  OG788_RS12290 (OG788_12320) - 2788744..2789922 (-) 1179 WP_406370684.1 GAF domain-containing sensor histidine kinase -
  OG788_RS12295 (OG788_12325) - 2790110..2790805 (+) 696 WP_351556228.1 SDR family NAD(P)-dependent oxidoreductase -
  OG788_RS12300 (OG788_12330) - 2790802..2791929 (+) 1128 WP_406370686.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG788_RS12305 (OG788_12335) - 2792222..2793001 (+) 780 WP_406370688.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22830.13 Da        Isoelectric Point: 5.1526

>NTDB_id=670050 OG788_RS12285 WP_266757150.1 2788110..2788751(-) (vraR) [Streptomyces sp. NBC_00647]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEASDGAEGVARAEELKPDVVLMDVKMPGMDGIDALRKLRELANPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEEANSGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRNGIAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=670050 OG788_RS12285 WP_266757150.1 2788110..2788751(-) (vraR) [Streptomyces sp. NBC_00647]
GTGGCTGACGCAATCAAGGTGCTGCTCGTCGACGACCACCAGGTCGTCCGCCGGGGCCTGCGTACCTTCCTCGAAGTGCA
GGACGACATCGAGGTCGTCGGAGAGGCGTCCGACGGTGCGGAAGGAGTCGCCCGCGCCGAGGAGCTGAAACCCGACGTCG
TCCTCATGGACGTGAAGATGCCGGGGATGGACGGCATCGACGCGCTGCGCAAGCTCCGTGAACTCGCCAACCCCGCACGG
GTGCTGATCGTCACCAGCTTCACCGAGCAGCGCACGGTGGTGCCGGCTCTGCGCGCGGGTGCCGCCGGTTACGTCTACAA
GGACGTGGATCCCGACGCGCTGGCCGGAGCCATCCGCTCGGTCCACGCCGGGCACATCCTGCTCCAACCCGAGGTCGCGG
GCGCCTTGTTGTCCCAGGAGGAGGCCAACTCGGGTCAGGGGAGAGGTGGTTCTCTCACCGAGCGGGAGCGCGAGGTGCTC
GGCCTGATCGCGGACGGCCGCTCCAACCGGGAGATCGCCCGCGCCCTCGTCCTCTCCGAGAAGACGGTGAAGACCCACGT
TTCGAACATCCTGATGAAGCTCGACCTCGCCGACCGCACCCAGGCCGCCCTCTGGGCCGTCCGTAACGGGATCGCGGGCT
GA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(151-206)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.024

99.061

0.446
  degU Bacillus subtilis subsp. subtilis str. 168

38.462

100

0.399