Detailed information NTG0669503

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: MTP23_RS05570
• Genome accession: NZ_CP094443
• Coordinates: 1102887..1103873 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain N10CSA27
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1097887..1108873

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MTP23_RS05545 (MTP23_05545)	-	1098147..1098494 (-)	348	WP_001242103.1	hypothetical protein	-
MTP23_RS05550 (MTP23_05550)	-	1098680..1099273 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
MTP23_RS05555 (MTP23_05555)	-	1099377..1099742 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
MTP23_RS05560 (MTP23_05560)	yjbH	1099765..1100571 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
MTP23_RS05565 (MTP23_05565)	pepF	1101031..1102839 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
MTP23_RS05570 (MTP23_05570)	coiA	1102887..1103873 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
MTP23_RS05575 (MTP23_05575)	mecA	1103994..1104713 (-)	720	WP_001217728.1	adaptor protein MecA	-
MTP23_RS05580 (MTP23_05580)	spxA	1105084..1105479 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
MTP23_RS05585 (MTP23_05585)	trpS	1105773..1106762 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
MTP23_RS05590 (MTP23_05590)	opp4C	1106804..1107685 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
MTP23_RS05595 (MTP23_05595)	opp4B	1107697..1108659 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=669503 MTP23_RS05570 WP_000959282.1 1102887..1103873(-) (coiA) [Staphylococcus aureus strain N10CSA27]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=669503 MTP23_RS05570 WP_000959282.1 1102887..1103873(-) (coiA) [Staphylococcus aureus strain N10CSA27]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976