Detailed information NTG0668656

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: MRS49_RS06775
• Genome accession: NZ_CP094294
• Coordinates: 1305671..1306834 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain AP3
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1300671..1311834

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MRS49_RS06745	-	1300935..1301354 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
MRS49_RS06750	comFC	1301428..1302117 (-)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
MRS49_RS06755	-	1302123..1302407 (-)	285	WP_003151389.1	competence protein ComFB	-
MRS49_RS06760	comFA	1302465..1303850 (-)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
MRS49_RS06765	-	1303959..1304807 (-)	849	WP_032876160.1	DegV family protein	-
MRS49_RS06770	degU	1304905..1305594 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
MRS49_RS06775	degS	1305671..1306834 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
MRS49_RS06780	-	1307057..1307704 (+)	648	WP_007614107.1	YigZ family protein	-
MRS49_RS06785	-	1307709..1308890 (+)	1182	WP_032876157.1	LCP family protein	-
MRS49_RS06790	-	1308989..1310065 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
MRS49_RS06795	-	1310198..1311394 (-)	1197	WP_032876154.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=668656 MRS49_RS06775 WP_007407484.1 1305671..1306834(-) (degS) [Bacillus velezensis strain AP3]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=668656 MRS49_RS06775 WP_007407484.1 1305671..1306834(-) (degS) [Bacillus velezensis strain AP3]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951