Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   MP387_RS07565 Genome accession   NZ_CP094226
Coordinates   1541352..1542041 (-) Length   229 a.a.
NCBI ID   WP_242746013.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1536352..1547041
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS07545 (MP387_07545) - 1537323..1538330 (-) 1008 WP_242745997.1 phosphomevalonate kinase -
  MP387_RS07550 (MP387_07550) mvaD 1538317..1539270 (-) 954 WP_242745999.1 diphosphomevalonate decarboxylase -
  MP387_RS07555 (MP387_07555) mvk 1539252..1540130 (-) 879 WP_242746001.1 mevalonate kinase -
  MP387_RS07560 (MP387_07560) cbpJ 1540248..1541252 (-) 1005 WP_242746009.1 N-acetylmuramoyl-L-alanine amidase family protein -
  MP387_RS07565 (MP387_07565) covR 1541352..1542041 (-) 690 WP_242746013.1 response regulator transcription factor Regulator
  MP387_RS07570 (MP387_07570) gndA 1542053..1543477 (-) 1425 WP_000158778.1 NADP-dependent phosphogluconate dehydrogenase -
  MP387_RS07575 (MP387_07575) - 1543553..1544998 (-) 1446 WP_242746015.1 cell division site-positioning protein MapZ family protein -
  MP387_RS07580 (MP387_07580) - 1545011..1546168 (-) 1158 WP_242746017.1 class I SAM-dependent RNA methyltransferase -
  MP387_RS07590 (MP387_07590) gpsB 1546654..1546983 (-) 330 WP_000146523.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26855.06 Da        Isoelectric Point: 8.0271

>NTDB_id=668119 MP387_RS07565 WP_242746013.1 1541352..1542041(-) (covR) [Streptococcus oralis strain 1648]
MVKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNARLGDMTAQDFAERLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=668119 MP387_RS07565 WP_242746013.1 1541352..1542041(-) (covR) [Streptococcus oralis strain 1648]
ATGGTGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTCGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGAGAGGCTGAGTCGGACAAAACCAGCCTCAGTGATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATAATCTAGTAGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTCATTGACCAACACTGTAGTCAAATGAAGGTTC
CAACGTCTTACCGCAACCTACGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGT
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467

Multiple sequence alignment