Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPF93_RS00735 Genome accession   NZ_CP094178
Coordinates   152368..153111 (+) Length   247 a.a.
NCBI ID   WP_245073946.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe060     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 147368..158111
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPF93_RS00710 (MPF93_00710) panD 149518..149868 (+) 351 WP_000142272.1 aspartate 1-decarboxylase -
  MPF93_RS00715 (MPF93_00715) - 149879..150172 (+) 294 WP_000347923.1 YbaB/EbfC family nucleoid-associated protein -
  MPF93_RS00720 (MPF93_00720) - 150172..151167 (+) 996 WP_245073942.1 PDZ domain-containing protein -
  MPF93_RS00725 (MPF93_00725) comB6 151175..152230 (+) 1056 WP_245073944.1 P-type conjugative transfer protein TrbL Machinery gene
  MPF93_RS00730 (MPF93_00730) comB7 152246..152371 (+) 126 WP_001217865.1 hypothetical protein Machinery gene
  MPF93_RS00735 (MPF93_00735) comB8 152368..153111 (+) 744 WP_245073946.1 virB8 family protein Machinery gene
  MPF93_RS00740 (MPF93_00740) comB9 153111..154073 (+) 963 WP_180506423.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPF93_RS00745 (MPF93_00745) comB10 154066..155202 (+) 1137 WP_245073948.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPF93_RS00750 (MPF93_00750) - 155268..156671 (+) 1404 WP_245073950.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPF93_RS00755 (MPF93_00755) gmd 156695..157840 (+) 1146 WP_245073952.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28691.90 Da        Isoelectric Point: 8.9546

>NTDB_id=668052 MPF93_RS00735 WP_245073946.1 152368..153111(+) (comB8) [Helicobacter pylori strain Hpfe060]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIAFVLAVVLISVLPLQKT
EHHFVDFLNQEKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=668052 MPF93_RS00735 WP_245073946.1 152368..153111(+) (comB8) [Helicobacter pylori strain Hpfe060]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAGTGATTTGGACATGCAAAGCGTGTTCAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAGCTCTTAGGCTTGATGAGTTTTATCGCTTTTGTTTTAGCGGTTGTTTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAAGAAAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCAGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTTACTCGCTACAGCATCACTGAAATC
GCACCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.356

100

0.964

Multiple sequence alignment