Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG60_RS00725 Genome accession   NZ_CP094177
Coordinates   151914..152657 (+) Length   247 a.a.
NCBI ID   WP_180483742.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe062     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 146914..157657
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG60_RS00700 (MPG60_00700) panD 149076..149426 (+) 351 WP_015428297.1 aspartate 1-decarboxylase -
  MPG60_RS00705 (MPG60_00705) - 149437..149730 (+) 294 WP_154411272.1 YbaB/EbfC family nucleoid-associated protein -
  MPG60_RS00710 (MPG60_00710) - 149730..150725 (+) 996 WP_245085691.1 PDZ domain-containing protein -
  MPG60_RS00715 (MPG60_00715) comB6 150733..151788 (+) 1056 WP_057112300.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG60_RS00720 (MPG60_00720) comB7 151804..151917 (+) 114 WP_073422943.1 comB7 lipoprotein Machinery gene
  MPG60_RS00725 (MPG60_00725) comB8 151914..152657 (+) 744 WP_180483742.1 virB8 family protein Machinery gene
  MPG60_RS00730 (MPG60_00730) comB9 152657..153622 (+) 966 WP_245084823.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG60_RS00735 (MPG60_00735) comB10 153615..154751 (+) 1137 WP_245084826.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG60_RS00740 (MPG60_00740) - 154821..156233 (+) 1413 WP_245084829.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG60_RS00745 (MPG60_00745) gmd 156247..157392 (+) 1146 WP_245084831.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28699.97 Da        Isoelectric Point: 8.9546

>NTDB_id=668031 MPG60_RS00725 WP_180483742.1 151914..152657(+) (comB8) [Helicobacter pylori strain Hpfe062]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
VPTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=668031 MPG60_RS00725 WP_180483742.1 151914..152657(+) (comB8) [Helicobacter pylori strain Hpfe062]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAGTGATTTGGACATGCAAAGCGTGTTCAGACTGGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTTTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCTATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGGGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGTTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATTGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCAAGCGT
TTCTATTGCGGCTAAACTCATGAATGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCCAAAAACCCTACCGGCTTTAAAATCACTCGTTACAGCATCACTGAAATC
GTGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.571

100

0.976

Multiple sequence alignment