Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG77_RS02235 Genome accession   NZ_CP094159
Coordinates   482515..483258 (+) Length   247 a.a.
NCBI ID   WP_245109903.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe0020     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 477515..488258
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG77_RS02210 (MPG77_02210) panD 479667..480017 (+) 351 WP_000142212.1 aspartate 1-decarboxylase -
  MPG77_RS02215 (MPG77_02215) - 480028..480321 (+) 294 WP_000347916.1 YbaB/EbfC family nucleoid-associated protein -
  MPG77_RS02220 (MPG77_02220) - 480321..481316 (+) 996 WP_245110191.1 PDZ domain-containing protein -
  MPG77_RS02225 (MPG77_02225) comB6 481322..482377 (+) 1056 WP_245110192.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG77_RS02230 (MPG77_02230) comB7 482393..482518 (+) 126 WP_001217874.1 hypothetical protein Machinery gene
  MPG77_RS02235 (MPG77_02235) comB8 482515..483258 (+) 744 WP_245109903.1 virB8 family protein Machinery gene
  MPG77_RS02240 (MPG77_02240) comB9 483258..484220 (+) 963 WP_245109904.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG77_RS02245 (MPG77_02245) comB10 484213..485349 (+) 1137 WP_245109906.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG77_RS02250 (MPG77_02250) - 485419..486831 (+) 1413 WP_245109907.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG77_RS02255 (MPG77_02255) gmd 486846..487991 (+) 1146 WP_245109909.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28669.90 Da        Isoelectric Point: 9.2603

>NTDB_id=667771 MPG77_RS02235 WP_245109903.1 482515..483258(+) (comB8) [Helicobacter pylori strain Hpfe0020]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAVVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFENLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=667771 MPG77_RS02235 WP_245109903.1 482515..483258(+) (comB8) [Helicobacter pylori strain Hpfe0020]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGGTTGTTTTAATCAGTGTTTTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGGGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAAATTTGATCAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCGGCTAAACTCATGAATGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTTACTCGCTACAGCATCACTGAAATC
GCGCCAACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.356

100

0.964

Multiple sequence alignment