Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   MPG02_RS07005 Genome accession   NZ_CP094142
Coordinates   1461198..1463561 (-) Length   787 a.a.
NCBI ID   WP_245075303.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe033     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1456198..1468561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG02_RS06980 (MPG02_06980) lpxE 1456715..1457260 (+) 546 WP_245075971.1 lipid A 1-phosphatase LpxE -
  MPG02_RS06985 (MPG02_06985) nspC 1457257..1458474 (-) 1218 WP_245075302.1 carboxynorspermidine decarboxylase -
  MPG02_RS06990 (MPG02_06990) cheV1 1458471..1459436 (-) 966 WP_180386895.1 chemotaxis protein CheV1 -
  MPG02_RS06995 (MPG02_06995) - 1459537..1460877 (-) 1341 WP_180406650.1 hypothetical protein -
  MPG02_RS07005 (MPG02_07005) comB4 1461198..1463561 (-) 2364 WP_245075303.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  MPG02_RS07010 (MPG02_07010) comB3 1463564..1463827 (-) 264 WP_048944994.1 hypothetical protein Machinery gene
  MPG02_RS07015 (MPG02_07015) comB2 1463827..1464108 (-) 282 WP_020971705.1 TrbC/VirB2 family protein Machinery gene
  MPG02_RS07020 (MPG02_07020) - 1464253..1465080 (-) 828 WP_154423423.1 DUF5718 family protein -
  MPG02_RS07025 (MPG02_07025) - 1465171..1466223 (-) 1053 WP_021306479.1 MnmA/TRMU family protein -
  MPG02_RS07030 (MPG02_07030) dnaG 1466220..1467899 (-) 1680 WP_245075304.1 DNA primase -
  MPG02_RS07035 (MPG02_07035) groES 1468174..1468530 (+) 357 WP_000671953.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90103.80 Da        Isoelectric Point: 9.1896

>NTDB_id=667523 MPG02_RS07005 WP_245075303.1 1461198..1463561(-) (comB4) [Helicobacter pylori strain Hpfe033]
MLEKLLSAIKQKVSNYFLGVLPKSYSMSEENNILGLYDKHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDHQQNIQTNSKYLQAILNQFENKEVYENQYFLVLESAHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSTTFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSVNKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDAQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLIIGATGSGKSTLISFLMMSALKYQNMHLLAFDRMQGL
YSFTKFFKGHYHDGKSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAILGAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSSAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNAKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPKEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=667523 MPG02_RS07005 WP_245075303.1 1461198..1463561(-) (comB4) [Helicobacter pylori strain Hpfe033]
ATGTTAGAAAAGCTTTTGAGTGCTATCAAACAAAAAGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATAAGCATTTCTTACTCACTAAAAACGAAAACTTGGTGGGCATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACGGAGCAATTGCAAGATCTCTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCGCGCCTTGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAATATCCAAACCAATTCCAA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAATAAAGAAGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCGCGC
ATTCTTTACAGGGCGTTTTAGAGCATAAGAAAAAATCTCTTATGCATGCCAATAGGGAAAATTTTAAGGACATCCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCTTAGAAATCCAGCTCAAAAACTACGCCCCCAAACTCTTAAGCTC
CAAAGAGGTTTTGAATTTTTATGCGGAATACATTAATGGGTTTGATCTCCCCCTAAAGCCCCTAGTAGGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTACCACTTTTGAAAAAGATTATTTCATTCAAGAAAGTTTTAACCAAAAAACCTACAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACGCC
ACTAGATATTATCTTTTCTATAGAGCCTATGAGTGTCAATAAAACGCTGAGTTTTTTAAAAGAGAGAGCCAAATTTAGCA
TGTCTAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAATTAGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACATTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACCAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTAAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTGAACC
ACCGCTTGCGCTTTTTAACTTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAACTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAACAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACCTTAATTATAGGGGCTACCGGGAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCACCTTTTAGCATTTGATAGGATGCAAGGGCTG
TATTCTTTCACAAAATTTTTTAAAGGGCATTACCATGACGGCAAATCTTTTAGCATCAACCCCTTTTGCTTAGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTTGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTTGGGCGCGATTAAGAGTCTTTATGAGACTTTATACCCTAAAGCTTTTAGTTTGCTAGACTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGTTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
CTTGAATGACGCGTTCAACTCCAGCGCTTTTTTAAATGTGATAAACCTAGATGCCATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAAATCTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTGTTGAACGCTAAAATTAACGCTTTAATCACGCAAGCTAGAAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGACATTTACCAATTAAGTGGGGTTAAAAACGCCCATAGTTTTTTAAGCAACATGGGAA
CTCTTATTTTGTACCCGCAAAAAAACGCTAGGGAGTTGAAACACCATTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCTAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAGTTCTAACATGATTGATGT
GAGTTTGGAGGGTTTGGGGCGTTATTTGAAAATCTTTAATTCAGACTCTAGCCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTAAAGAGTGGCGTGAGAAACTTTTAAAGAGCTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-468)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

96.95

100

0.97

Multiple sequence alignment