Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG74_RS00930 Genome accession   NZ_CP094120
Coordinates   194652..195395 (+) Length   247 a.a.
NCBI ID   WP_245069719.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe061     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 189652..200395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG74_RS00905 (MPG74_00905) panD 191814..192164 (+) 351 WP_245069717.1 aspartate 1-decarboxylase -
  MPG74_RS00910 (MPG74_00910) - 192175..192468 (+) 294 WP_000347923.1 YbaB/EbfC family nucleoid-associated protein -
  MPG74_RS00915 (MPG74_00915) - 192468..193463 (+) 996 WP_245070253.1 PDZ domain-containing protein -
  MPG74_RS00920 (MPG74_00920) comB6 193471..194526 (+) 1056 WP_245070255.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG74_RS00925 (MPG74_00925) comB7 194542..194655 (+) 114 WP_001217877.1 hypothetical protein Machinery gene
  MPG74_RS00930 (MPG74_00930) comB8 194652..195395 (+) 744 WP_245069719.1 virB8 family protein Machinery gene
  MPG74_RS00935 (MPG74_00935) comB9 195395..196357 (+) 963 WP_180577520.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG74_RS00940 (MPG74_00940) comB10 196350..197486 (+) 1137 WP_245069722.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG74_RS00945 (MPG74_00945) - 197552..198967 (+) 1416 WP_245069724.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG74_RS00950 (MPG74_00950) gmd 198978..200123 (+) 1146 WP_001918970.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28672.86 Da        Isoelectric Point: 8.9546

>NTDB_id=667128 MPG74_RS00930 WP_245069719.1 194652..195395(+) (comB8) [Helicobacter pylori strain Hpfe061]
MKEKPFNSEQLNYLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=667128 MPG74_RS00930 WP_245069719.1 194652..195395(+) (comB8) [Helicobacter pylori strain Hpfe061]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGAACTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAGTGATTTGGACATGCAAAGCGTGTTCAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATTGTTTTAATCAGTGTTTTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAGGATTTGATCAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCAGCTAAACTCATGAATGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.571

100

0.976

Multiple sequence alignment