Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG48_RS00720 Genome accession   NZ_CP094113
Coordinates   149679..150416 (+) Length   245 a.a.
NCBI ID   WP_245065411.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe069     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 144679..155416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG48_RS00695 (MPG48_00695) panD 146831..147181 (+) 351 WP_000142208.1 aspartate 1-decarboxylase -
  MPG48_RS00700 (MPG48_00700) - 147192..147485 (+) 294 WP_000347922.1 YbaB/EbfC family nucleoid-associated protein -
  MPG48_RS00705 (MPG48_00705) - 147485..148480 (+) 996 WP_245065928.1 PDZ domain-containing protein -
  MPG48_RS00710 (MPG48_00710) comB6 148486..149541 (+) 1056 WP_245065930.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG48_RS00715 (MPG48_00715) comB7 149557..149682 (+) 126 WP_001217867.1 hypothetical protein Machinery gene
  MPG48_RS00720 (MPG48_00720) comB8 149679..150416 (+) 738 WP_245065411.1 virB8 family protein Machinery gene
  MPG48_RS00725 (MPG48_00725) comB9 150416..151378 (+) 963 WP_245065412.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG48_RS00730 (MPG48_00730) comB10 151371..152507 (+) 1137 WP_245065413.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG48_RS00735 (MPG48_00735) - 152577..153989 (+) 1413 WP_245065414.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG48_RS00740 (MPG48_00740) gmd 154003..155148 (+) 1146 WP_245065415.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28530.74 Da        Isoelectric Point: 8.9546

>NTDB_id=667023 MPG48_RS00720 WP_245065411.1 149679..150416(+) (comB8) [Helicobacter pylori strain Hpfe069]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAVVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIVAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
TNRGD

Nucleotide


Download         Length: 738 bp        

>NTDB_id=667023 MPG48_RS00720 WP_245065411.1 149679..150416(+) (comB8) [Helicobacter pylori strain Hpfe069]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTCTAAGCCATCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGGTTGTTTTAATCAGTGTTTTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATCAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCTATTGTGGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTTACTCGCTACAGCATCACTGAAATC
ACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

95.547

100

0.963

Multiple sequence alignment