Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG37_RS00740 Genome accession   NZ_CP094064
Coordinates   154984..155727 (+) Length   247 a.a.
NCBI ID   WP_140563071.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe114     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 149984..160727
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG37_RS00715 (MPG37_00715) panD 152134..152484 (+) 351 WP_180461662.1 aspartate 1-decarboxylase -
  MPG37_RS00720 (MPG37_00720) - 152495..152788 (+) 294 WP_000347922.1 YbaB/EbfC family nucleoid-associated protein -
  MPG37_RS00725 (MPG37_00725) - 152788..153783 (+) 996 WP_245051718.1 PDZ domain-containing protein -
  MPG37_RS00730 (MPG37_00730) comB6 153791..154846 (+) 1056 WP_245051720.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG37_RS00735 (MPG37_00735) comB7 154862..154987 (+) 126 WP_001217874.1 hypothetical protein Machinery gene
  MPG37_RS00740 (MPG37_00740) comB8 154984..155727 (+) 744 WP_140563071.1 virB8 family protein Machinery gene
  MPG37_RS00745 (MPG37_00745) comB9 155727..156689 (+) 963 WP_245051203.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG37_RS00750 (MPG37_00750) comB10 156682..157818 (+) 1137 WP_245051204.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG37_RS00755 (MPG37_00755) - 157888..159300 (+) 1413 WP_245051209.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG37_RS00760 (MPG37_00760) gmd 159314..160459 (+) 1146 WP_245051210.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28732.96 Da        Isoelectric Point: 8.9546

>NTDB_id=666307 MPG37_RS00740 WP_140563071.1 154984..155727(+) (comB8) [Helicobacter pylori strain Hpfe114]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIAFILAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=666307 MPG37_RS00740 WP_140563071.1 154984..155727(+) (comB8) [Helicobacter pylori strain Hpfe114]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAGAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTAGACTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGTTTGATGAGTTTTATCGCTTTTATCTTAGCGATCGTGTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCTATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATCAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCGGCTAAACTCATGAACGAAAACAAACTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.972