Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SCSC_RS06965 Genome accession   NZ_AP014647
Coordinates   1427613..1428302 (-) Length   229 a.a.
NCBI ID   WP_006269448.1    Uniprot ID   A0AAD2SXA0
Organism   Streptococcus constellatus subsp. constellatus strain CCUG 24889     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1422613..1433302
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCSC_RS06945 (SCSC_1425) nrdR 1423174..1423647 (-) 474 WP_006269445.1 transcriptional regulator NrdR -
  SCSC_RS06950 (SCSC_1426) - 1423846..1424334 (+) 489 WP_006269443.1 hypothetical protein -
  SCSC_RS06955 (SCSC_1427) - 1424381..1425196 (-) 816 WP_006269465.1 endonuclease/exonuclease/phosphatase family protein -
  SCSC_RS06960 (SCSC_1428) - 1425213..1427402 (-) 2190 WP_037565534.1 PTS transporter subunit IIBC -
  SCSC_RS06965 (SCSC_1430) covR 1427613..1428302 (-) 690 WP_006269448.1 response regulator transcription factor Regulator
  SCSC_RS06970 (SCSC_1431) gndA 1428311..1429735 (-) 1425 WP_006269467.1 NADP-dependent phosphogluconate dehydrogenase -
  SCSC_RS06975 (SCSC_1432) - 1429940..1430605 (+) 666 WP_006269469.1 TetR/AcrR family transcriptional regulator -
  SCSC_RS06980 (SCSC_1433) - 1430595..1431329 (+) 735 WP_003029928.1 ATP-binding cassette domain-containing protein -
  SCSC_RS06985 (SCSC_1434) - 1431313..1432041 (+) 729 WP_006269451.1 ABC transporter permease -
  SCSC_RS06990 - 1432041..1432268 (+) 228 WP_003029926.1 hypothetical protein -
  SCSC_RS06995 (SCSC_1435) - 1432535..1433074 (-) 540 WP_006270463.1 YceD family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26545.64 Da        Isoelectric Point: 6.1329

>NTDB_id=66573 SCSC_RS06965 WP_006269448.1 1427613..1428302(-) (covR) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MGKRILLVENEKKLAQFICLELQNEGYRVDLLETGKDALASARANQYDLFLLNFMLEDMTGTEFAEQLSLIKPASVIIVL
DNRDIILKYTEEIQRFAVSYMIEPFIAMDLVEKISAIFRGRDFIDHHCSQMKVSTSYRNLRIDVQNHTVYRGNEIISLTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKLDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=66573 SCSC_RS06965 WP_006269448.1 1427613..1428302(-) (covR) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGGGGAAGCGGATTTTATTAGTTGAGAATGAAAAAAAATTAGCACAATTTATTTGCTTAGAGTTGCAAAATGAAGGTTA
TCGAGTGGATCTTCTTGAAACGGGAAAAGATGCTTTAGCATCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGAAGATATGACAGGAACGGAGTTTGCTGAGCAATTAAGTTTGATAAAGCCTGCTTCAGTCATTATTGTATTG
GATAATCGTGATATTATTTTAAAATATACTGAGGAAATCCAACGTTTTGCTGTTAGTTATATGATAGAGCCTTTCATTGC
GATGGACTTGGTCGAAAAAATTTCTGCTATTTTTCGTGGGCGTGATTTTATTGATCATCATTGTAGTCAGATGAAAGTTT
CAACATCTTATCGGAATCTTCGCATTGACGTGCAAAATCATACTGTATATCGAGGGAATGAAATAATTTCCTTGACTAGA
AGAGAGTATGATTTGTTAGCAACGCTGATGGGCAGTCATCAGGCTTTAAGCCGTGAACAGCTGTTAGAGCGCGTTTGGAA
ATACGAAGGAGCAGTTGAAACAAATGTTGTTGATGTCTATATTCGTTATCTTCGTAGTAAACTTGATATAGCAGGGCAGA
AAAGTTACATAAAAACCGTGCGTGGTGTTGGCTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-227)

Response regulator receiver domain (Response_reg)

(5-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.737

99.563

0.445

Multiple sequence alignment