Detailed information NTG0066566

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: SCSC_RS04875
• Genome accession: NZ_AP014647
• Coordinates: 986525..987757 (-)
• Length: 410 a.a.
• NCBI ID: WP_003068865.1
• Uniprot ID: A0AAD2SY77
• Organism: Streptococcus constellatus subsp. constellatus strain CCUG 24889
• Function: require for competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	977463..989621	986525..987757	within	0

Gene organization within MGE regions

Location: 977463..989621

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCSC_RS04840 (SCSC_1001)	-	977463..978203 (+)	741	WP_006269402.1	amino acid ABC transporter ATP-binding protein	-
SCSC_RS04845 (SCSC_1002)	-	978578..980113 (+)	1536	WP_006269421.1	ATP-binding cassette domain-containing protein	-
SCSC_RS04850 (SCSC_1003)	-	980232..981980 (-)	1749	WP_006269410.1	ABC transporter ATP-binding protein	-
SCSC_RS04855 (SCSC_1004)	-	981961..983706 (-)	1746	WP_006269393.1	ABC transporter ATP-binding protein	-
SCSC_RS04860 (SCSC_1005)	-	983920..984717 (-)	798	WP_006269368.1	formate/nitrite transporter family protein	-
SCSC_RS04865 (SCSC_1006)	-	984893..985600 (-)	708	WP_003068871.1	glucosaminidase domain-containing protein	-
SCSC_RS04870 (SCSC_1007)	yihA	985925..986512 (-)	588	WP_006269383.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
SCSC_RS04875 (SCSC_1008)	clpX	986525..987757 (-)	1233	WP_003068865.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
SCSC_RS04880 (SCSC_1009)	-	987811..987984 (-)	174	WP_003024903.1	hypothetical protein	-
SCSC_RS04885 (SCSC_1010)	-	987984..988496 (-)	513	WP_003068862.1	dihydrofolate reductase	-
SCSC_RS04890 (SCSC_1011)	-	988782..989621 (-)	840	WP_003068859.1	thymidylate synthase	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45677.14 Da
• Isoelectric Point: 4.3940

>NTDB_id=66566 SCSC_RS04875 WP_003068865.1 986525..987757(-) (clpX) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MPTNRTSEMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDNREEEDDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDENSSYMQEIISEDIQKFGLIPELIGRLPVFAALEPLTVDDLVR
ILREPKNALVKQYQTLLSYDDVTLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide

• Length: 1233 bp

>NTDB_id=66566 SCSC_RS04875 WP_003068865.1 986525..987757(-) (clpX) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGCCTACAAATCGTACGAGCGAAATGATGGTTTATTGTTCTTTTTGTGGTAAAAGTCAAGAAGAAGTTCAAAAAATTAT
TGCAGGAAACAATGCATTTATTTGTAACGAATGTGTGGAATTAGCACAAGAAATTATTAGAGAAGAATTAGCAGAAGAAG
TCTTGGCAGACTTGTCGGAAGTACCAAAACCACAAGAATTGCTTAACATTTTAAATCACTATGTAATAGGGCAAGATCGT
GCAAAGCGAGCGCTGGCTGTTGCTGTATACAATCACTATAAACGTATCAATTTTCACGATAATCGTGAAGAAGAGGATGA
TGTCGAATTACAAAAATCCAATATTCTTATGATTGGTCCAACCGGTTCAGGTAAGACTTTTCTTGCTCAAACTTTAGCGA
AAAGTCTAAATGTTCCCTTTGCGATTGCAGATGCGACAGCTTTGACGGAAGCTGGCTATGTCGGGGAAGATGTTGAAAAC
ATTCTCTTAAAACTCTTGCAAGCTGCAGATTTTAATATTGAGCGTGCAGAACGTGGCATTATCTATGTAGATGAGATTGA
CAAAATTGCAAAGAAAAGCGAAAACGTCTCTATTACTCGTGATGTGTCTGGTGAAGGCGTTCAGCAAGCTTTGCTTAAAA
TCATTGAAGGGACTGTAGCTAGTGTACCTCCTCAAGGCGGTCGCAAACATCCACAGCAAGAAATGATTCAAGTGGATACC
AAGAATATTCTTTTTATCGTTGGCGGTGCTTTTGACGGAATCGAAGAAATCGTCAAACAACGTCTAGGTGAAAAGATCAT
TGGTTTTGGTCAAAATAACAAAGCTATTGATGAAAATAGTTCTTATATGCAAGAAATTATTTCCGAAGATATTCAAAAAT
TTGGGCTTATTCCTGAATTGATTGGTCGTTTGCCTGTGTTTGCAGCGCTTGAGCCTTTGACTGTTGATGATTTGGTGCGA
ATTCTCCGTGAGCCTAAGAATGCTTTAGTGAAACAATATCAAACGCTTCTTTCTTATGACGATGTTACATTAGAGTTTGA
TGATGATGCTCTCCAAGAGATTGCTAACAAAGCTATTGAACGCAAGACAGGCGCTCGTGGCTTGCGCTCGATTATCGAAG
AAACCATGATGGATGTCATGTTTGAAGTACCAAGTCAAGAAAATGTGAAGTTAGTGCGGATTACCAAGGAAGCAGTTGAT
GGAACAGATAAACCGATTTTAGAAACAGCTTAA

Domains

Predicted by InterproScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (313-390)

• AAA domain (Cdc48 subfamily) (AAA_2) (111-306)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	86.585	100	0.866
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.458	98.049	0.573